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the goal of this observational study is to evaluate the role of VEXUS score and lung ultrasound to guide decongestive therapy in patients with cardiorenal syndrome type -1. the main question it aims to answer is: Can the VEXUS score and lung ultrasound guide the efffect of decongestive therapy on KFR and decongestion metrics in patients with CRS-1 compared to standard assesment ?
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| the VEXUS group :in this group we use the vexus score to guide decongestive theapy | Active Comparator | the use of diuretic if vexus score more than 1 at time of enrollement |
|
| the lung US group : we use lung ultrasound score to detect degree of pulmonary congestion | Active Comparator | if lung ultrasound score more than 15 we will start diuretic therapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| frusemide | Drug | in this group we use vexus score to asses decongestion in comparison to lung ultrasound in other group |
|
| Measure | Description | Time Frame |
|---|---|---|
| assesment of KFR using the KDIGO AKI staging improvement | stage1:serum creatinine increase 1,5 - 2 folds serum creatinine increase 2 - 3 folds serum creatinine increase more than 3 folds | 1 week |
| Measure | Description | Time Frame |
|---|---|---|
| VEXUS score | grade 1 : no congestion grade 2:mild congestion grade 3 moderate congestion grade 4 : severe congestion | 48 hours |
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Inclusion Criteria:
• Patients of both genders aged 18-65 years old.
Exclusion Criteria:
• Refusal to participate.
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| Name | Affiliation | Role |
|---|---|---|
| asmaa AS Behairy, master | Benha University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Asmaa Shahat Mohamedy Behairy | Cairo | Egypt |
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| ID | Term |
|---|---|
| D005665 | Furosemide |
| ID | Term |
|---|---|
| D013424 | Sulfanilamides |
| D013449 | Sulfonamides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
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| D000814 |
| Aniline Compounds |
| D000588 | Amines |
| D013450 | Sulfones |
| D013457 | Sulfur Compounds |