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Dietary protein intake is essential for tissue renewal and growth. Current recommendations for protein intake are based on studies using egg protein as reference protein. Egg protein is an animal-based protein with a high quality. Protein quality is determined by the composition of (essential) amino acids and digestibility. Therefore, different proteins have a different quality. Due to the environmental crisis, an increasing number of people consumes more plant-based proteins. These plant-based proteins often have a lower protein quality compared to animal-based proteins. Therefore, the aim of this study is to investigate whether optimal protein intake depend on protein quality. The optimal protein intake of an animal-based protein with a high quality (milk) will be compared to the optimal protein intake of a plant-based protein with a low quality (wheat).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MILK | Active Comparator | Drink containing amino acid composition of milk protein |
|
| WHEAT | Active Comparator | Drink containing amino acid composition of wheat protein |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MILK | Other | Drink containing amino acids in the composition of milk protein |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Differences in protein intake to maximize whole-body protein synthesis rates in older adults based on consumption of milk protein or wheat protein | From enrollment to the end of the study at 7 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Estimated Average Requirement (EAR) to maximize whole-body protein synthesis rates in healthy older adults based on milk protein | From enrollment to the end of the study at 7 weeks | |
| The Recommended Daily Allowance (RDA) to maximize whole-body protein synthesis rates in older adults based on milk protein |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Luc van Loon | Contact | 0031 43 388 1743 | l.vanloon@maastrichtuniversity.nl |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Maastricht University Medical Center+ | Maastricht | Limburg | Netherlands |
Data will be made available upon request
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| ID | Term |
|---|---|
| D008892 | Milk |
| ID | Term |
|---|---|
| D001628 | Beverages |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D003611 | Dairy Products |
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Double-blind, randomized, parallel study design
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Protein beverages with milk- or wheat composition will look similar.
| WHEAT |
| Other |
Drink containing amino acids in the composition of wheat protein |
|
| From enrollment to the end of the study at 7 weeks |
| The Estimated Average Requirement (EAR) to maximize whole-body protein synthesis rates in older adults based on wheat protein | From enrollment to the end of the study at 7 weeks |
| The Recommended Daily Allowance (RDA) to maximize whole-body protein synthesis rates in older adults based on wheat protein | From enrollment to the end of the study at 7 weeks |
| D005502 |
| Food |
| D019602 | Food and Beverages |