Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study

Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study

The purpose of this research is to determine the feasibility of a larger, future study proposing a multimodal approach using cardiac CT and MRI to assess the risk of developing left ventricular (LV) systolic dysfunction in patients with mitral regurgitation (MR).

Inclusion Criteria:

• Age >= 18
• Male or Female
• A diagnosis of severe chronic primary mitral regurgitation
• Undergoing isolated robotic mitral annuloplasty at Mayo Clinic Rochester
• Patients must have the ability to consent or have an appropriate representative available to do so.

Exclusion Criteria:

• Prior valve intervention,
• Concomitant valve surgery at the time of mitral annuloplasty (e.g. tricuspid annuloplasty, aortic valve replacement).
• Concomitant >= moderate regurgitation or stenosis in any other valve by preoperative echocardiography
• History of prior myocardial infarction
• History of cardiomyopathy unrelated to mitral regurgitation (e.g. dilated, hypertrophic, infiltrative)
• Pregnancy. Women of childbearing potential will be verbally screened by clinical staff during as part of routine pre-MRI evaluation. If a subject is unsure whether they could be pregnant, a negative pregnancy test will be performed prior to scanning.
• Implantable devices that would be a contraindication to MRI
• Severe allergy to gadolinium MRI contrast