Platelet Rich Plasma (PRP) as Terapeutical Option in Erectil Disfunction (DE)

Platelet Rich Plasma (PRP) as Terapeutical Option in Erectil Disfunction (DE)

Patients are randomized into 2 groups (A and B), subsequently group A is subjected to a cycle of 6 weekly injections of 3 ml of autologous PRP while group B is subjected to 6 weekly injections of 1 ml of caverject (alprostadil) 20 mcg. After 4 (four) weeks the groups will be crossed, so group A will be subjected to 6 weekly injections of 1 ml of caverject (alprostadil) 20 mcg while group B will be subjected to a cycle of 6 weekly injections of 3 ml of autologous PRP.

Inclusion Criteria:

• Moderate to severe erectile dysfunction (IIEF-5 score below 17)
• Patients previously treated with first- and second-line therapies for ED
• Patients who have undergone radical pelvic surgery with nerve sparing
• Good pharmacological blood pressure control
• Well-controlled diabetes on medication
• Current or former smokers
• Good renal function even with the use of medications
• Well-controlled hypertriglyceridemia and/or hypercholesterolemia even with the use of medications
• BMI less than or equal to 35
• Normal levels of FSH, LH, PRL, Total Testosterone, and TSH

Exclusion Criteria:

• Patients on antidepressant, anxiolytic, sedative, or antipsychotic medications.
• Consumers of more than 500 g of alcohol per day.
• BMI greater than 35
• Altered levels of FSH, LH, PRL, Total Testosterone, and TSH.