The Rule of Bupivacaine Hydrochloride in Skin Graft Donor Site

Bupivacaine Hydrochloride-Soaked Dressing Versus Subcutaneous Infiltration for Postoperative Analgesia in Skin Graft Donor Site: a Randomized Controlled Clinical Trial

Split Thickness Skin Graft is frequently utilized for reconstructing skin loss of various causes. Unfortunately, the donor site of the STSG has an unavoidable, annoying post-operative pain

The primary objective of this study was to compare the efficacy of bupivacaine hydrochloride-soaked dressing versus bupivacaine HCL subcutaneous infiltration for postoperative donor site pain control for patients undergoing STSG procedures. The patients were divided in 3 equal groups, investigated soaked dressing vs subcutaneous infiltration vs conventional dressing .

Inclusion Criteria:

• American Society of Anesthesiologists Physical Status classification I-II
• scheduled for STSG harvested from a single thigh donor site to reconstruct skin loss post burn or trauma

Exclusion Criteria:

• uncooperative
• refusing patient,
• under immunosuppressive treatment
• diabetics
• lower-limb neuropathy
• under corticosteroids treatment
• allergy to the study drug,
• STSG procedures performed under spinal anesthesia
• pregnancy
• had a history of opioid abuse