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The aim of this observational study is to learn the effects of prone position duration on patient outcomes in patients with severe acute respiratory distress syndrome (ARDS) due to Coronavirus Disease - 2019 (COVID-19). The main question it aims to answer is:
Does the length of prone position duration affect gas exchange in patients with severe ARDS and is there a difference between genders in this regard? The differences in gas exchange between those who have been in prone position for 16-24 hours and those who have been in prone position for 24-36 hours as part of severe ARDS treatment will be examined.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Short Prone | The group of patients who remained in prone position for 16-24 hours | ||
| Long Prone | The group of patients who remained in prone position for 24-36 hours |
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| Measure | Description | Time Frame |
|---|---|---|
| Calculation of PaO2/FiO2 ratio during short and long prone periods | Partial arterial oxygen pressure/Fraction of inspired oxygen (PaO2/FiO2) ratio changes before, during and after pronation at each group will be calculated. | At each prone session, calculation will be started one hour before the pronation and finished one hour after returning supine. |
| Measure | Description | Time Frame |
|---|---|---|
| Measurement of PaCO2 during short and long prone periods | Partial arterial carbon dioxide pressure (PaCO2) changes before, during and after pronation at each group will be measured. | At each prone session, measurement will be started one hour before the pronation and finished one hour after returning supine. |
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Inclusion Criteria:
Exclusion Criteria:
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The study population consisted of Covid-19 ARDS patients hospitalized in the tertiary intensive care unit of a university hospital.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| İstanbul University - Cerrahpaşa, Cerrahpaşa Medical Faculty | Istanbul | 34153 | Turkey (Türkiye) |
Approval was not obtained from the institute's ethics committee for sharing patient data with an international registry.
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D012128 | Respiratory Distress Syndrome |
| D003075 | Coitus |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| Measurement of PEEP during short and long prone periods |
Positive end-expiratory pressure (PEEP) changes before, during and after pronation at each group will be measured. |
| At each prone session, measurement will be started one hour before the pronation and finished one hour after returning supine. |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D012120 | Respiration Disorders |
| D012725 | Sexual Behavior |
| D001519 | Behavior |