Intravenous Granisetron Vs Dexmedetomidine on Postspinal in the Cesarean Section.

The Effect of Intravenous Granisetron Versus Intravenous Dexmedetomidine on Shivering Following Spinal Anesthesia in the Cesarean Section. a Randomized Controlled Comparative Trial .

The Aim of this study is to investigate and compare the efficacy of intravenous Dexmedetomidine (0.3 ug/kg) versus intravenous Granisetron (3 mg) in the prevention of shivering in parturient undergoing cesarean section under spinal anesthesia.

Study groups:

Randomization will be done according to computer guided table with sealed closed envelopes prepared by the supervisor, All study drugs will be prepared by the supervisor. Each group will be 25 patients.

Inclusion Criteria:

• patients scheduled for cesarean section under spinal anesthesia.
• age : (20-45) years old.
• American Society of Anesthesia (ASA) physical status I, II.

Exclusion Criteria:

• Patient refusal.
• Contraindication to spinal anesthesia.
• BMI > 35 kg/m².
• Impaired renal, hepatic and cardiac function.
• Thyroid disease.
• Body temperature >38 °C or < 36.5 °C.