Efficacy of Hypochlorous Acid as a Postoperative Wound Antiseptic

Investigation of the Efficacy of Hypochlorous Acid as a Postoperative Wound Antiseptic: A Randomized Controlled Pilot Study

The aim was to examine the effectiveness of hypochlorous acid on postoperative wound healing in 24 systemically healthy gingivectomy participants aged 12-30. The participants were divided into 3 groups as hypochlorous acid group, chlorhexidine group and saline group and their wound healing was evaluated on the 1st, 3rd and 7th days.

The aim of this study was to investigate the effectiveness of hypochlorous acid on postoperative wound healing in 24 participants aged 12-30 who underwent gingivectomy involving the 6 anterior teeth of the upper or lower jaw with chronic inflammatory gingival overgrowth. The participants were divided into 3 groups as hypochlorous acid group, chlorhexidine group and saline group and were called for control on the 1st, 3rd and 7th days to evaluate wound healing. Periodontal indexes, visual analog scale (VAS), H2O2, plaque staining agent test, and histological analyzes were used to evaluate wound healing. The data were analyzed statistically.

Inclusion Criteria:

• Gingival overgrowth affecting at least six teeth symmetrically in the mandibular or maxillary anterior area
• No attachment and bone loss
• 7 days before the surgery, full-mouth plaque index (PI) < 25% and a full-mouth gingival bleeding index (GBI) < 25%.
• the keratinized tissues surrounding the teeth are at least 2 mm wide.

Exclusion Criteria:

• Smoking or alcohol use
• Patients who have undergone systemic antimicrobial therapy and surgical procedures within the last 3 months
• Pregnancy or lactation
• Immunodeficiency or immunosuppressive drug therapy