Autonomic Differences in Heart Rate Variability Between Healthy and Chronic Low Back Pain Subjects

Cross-Sectional Analysis of Autonomic Differences in Heart Rate Variability Between Healthy Individuals and Subjects with Chronic Low Back Pain

This study aims to evaluate the autonomic differences in heart rate variability (HRV) between healthy individuals and those with chronic low back pain. By analyzing HRV parameters, such as time-domain, frequency-domain, and non-linear metrics, this cross-sectional study seeks to explore the impact of chronic pain on the autonomic nervous system. The study will provide insights into parasympathetic and sympathetic modulation and its potential relationship with chronic pain symptoms. Participants include healthy adults and individuals with chronic low back pain aged 18-65.

Inclusion Criteria:

• Adults aged between 18 and 65 years.

For the chronic low back pain group:

• Diagnosis of chronic low back pain lasting at least three months.
• A minimum pain intensity of 3/10 on the Numerical Pain Rating Scale (NPRS).

For the healthy group:

• Absence of any chronic or acute pathology.
• No regular medication that could alter autonomic nervous system function.
• No episodes of low back pain in the past six months.

Exclusion Criteria:

• Presence of uncontrolled neurological or cardiac disorders.
• Use of medications that could influence autonomic function or pain perception (e.g., opioids, antidepressants, benzodiazepines, anti-inflammatory drugs, beta-blockers) within two weeks prior to the study.
• Body Mass Index (BMI) equal to or greater than 30 kg/m².