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| Name | Class |
|---|---|
| BG Klinik Murnau | UNKNOWN |
| BG Trauma Center Ludwigshafen | OTHER |
| BG Klinikum Duisburg | UNKNOWN |
| BG Klink Hamburg |
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At least ten percent of trauma patients suffer from any sort of complication. The study aims to identify a risk factor profile to early identify trauma patients at risk.
Trauma patients suffer from a high risk of complications that ranges from soft tissue complications, surgical site infection till bone non-union. Comorbidities are often know to be associated with complications. Also certain blood markers could be identified to be an indicator.
However, certain risk factors have only been investigated in small trauma cohorts so far. This study is a prospective multi center cohort trail that aims to collect all clinical data, comorbidities, medication, blood markers in trauma patients after long bone fractures. In a 6 months and one year follow up patients with complications will be identified. Methods of machine learning will help to identify a risk factor profile for certain groups of patients with complications.
The aim of the study is to early identify patients at risk for a complication after trauma according to their blood marker, clinical, comorbidity and medication profile.
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| Measure | Description | Time Frame |
|---|---|---|
| any complication after long bone fracture | number of patients that suffer from a complication after surgical treatment of a primary long bone fracture | 6 months, one year |
| Clavien Dindo Classification | Clavien Dindo Classification classifies surgical complications. All patients will be classified according to Clavien Dindo after 6 months and one year. | 6 months, one year |
| Measure | Description | Time Frame |
|---|---|---|
| Charlson Comorbidity Index (CCI) | Charlson Comorbidity Index classifies comorbidities of patients. All particiapants will be screened for their comorbidities and classified according to CCI. | Initially |
| number of medications |
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Inclusion Criteria:
Exclusion Criteria:
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patients that suffer from an acute lone bone fracture, require surgical treatment and belong to the age group of being able to working (18 - 67 years old)
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marie K Reumann, MD | Contact | +497071606 | 3113 | mreumann@bgu-tuebingen.de |
| Mika Rollmann, MD | Contact | +497071606 | 3002 | mrollmann@bgu-tuebingen.de |
| Name | Affiliation | Role |
|---|---|---|
| Marie K Reumann, MD | Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen | Tübingen | Baden-Wurttemberg | 72076 | Germany |
Data of all patients will be pseudonymised. No individual participant data will be identified.
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| UNKNOWN |
| Unfallkrankenhaus Berlin | OTHER |
| BG Ambulanz Bremen | UNKNOWN |
| Bundeswehrkrankenhaus Ulm | UNKNOWN |
| Paracelsus Universität Salzburg | UNKNOWN |
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blood
Intake of medication will be assessed and number of medication will be identified.
| initally |
| EuroQual 5 Dimensions Questionnaire (EQ5D5L) | EQ5D5L will be assessed from each participant to identify their quality of life. | initially, 6 months, one year. |
| patient reported outcome measure associated with the lone bone fracture | patient reported outcome measure will be assessed by each patient that is associated with the lone bone fracture | initially, 6 months, one year. |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D013530 | Surgical Wound Infection |
| D014946 | Wound Infection |
| D011542 | Pseudarthrosis |
| D011014 | Pneumonia |
| D003428 | Cross Infection |
| D014947 | Wounds and Injuries |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D007239 | Infections |
| D005599 | Fractures, Ununited |
| D050723 | Fractures, Bone |
| D012141 | Respiratory Tract Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D007049 | Iatrogenic Disease |
| D020969 | Disease Attributes |
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