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Evaluate the diagnostic accuracy of Magnetic Resonance Cholangiopancreatography (MRCP) compared with Ultrasound and Computed Tomography (CT) in patients with obstructive jaundice taking findings of ERCP/ PTC and histopathology as gold standard.
MRCP as a diagnostic role to determine the presence and severity of biliary and pancreatic ductal dilatation. It can also detect the length of the stricture as well as the exact cause and location of the obstructing lesion in comparison to other modalities.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients diagnosed with obstructive jaundice | MRCP as a role that is used as a non-invasive diagnostic tool for visualizing the pancreaticobiliary tree without the use of contrast media |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Magnetic Resonance Cholangiopancreatography | Diagnostic Test | Three most important sequences included axial T2 weighted scan from liver to ampullary region followed by T2 weighted 3D FSE sequence acquired in coronal oblique plane using respiratory triggering by tying bellows over abdomen. After this breath hold HASTE sequence is acquired in coronal plane. Maximum intensity projection (MIP) and thick slab images are also used for interpretation. US, CECT and MRCP scans are interpreted by radiologists blinded to other imaging findings |
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic accuracy of Magnetic Resonance Cholangiopancreatography in patients with obstructive jaundice according to the findings | Magnetic Resonance Cholangiopancreatography findings in patients with obstructive jaundice comparing to findings of ERCP/ PTC and histopathology . | Within twelve months |
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Inclusion Criteria:
Adult male and female patients clinically diagnosed obstructive jaundice are included in the study with positive laboratory tests.
Exclusion Criteria:
Patients with non-obstructive (prehepatic/hepatic) cause of jaundice. Patients having contraindications to perform MRI (Patients with any electrically, magnetically or mechanically activated implants, pacemaker, cochlear implants or any metallic orthopedic implants and claustrophobic patients).
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Adult male and female patients clinically diagnosed obstructive jaundice are included in the study with positive laboratory tests.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Demiana M Soliman, Resident | Contact | 01211992362 | r.demiana.mohsen@gmail.com | |
| Hisham A Amin, A. professor | Contact | +20 115 115 2564 |
| Name | Affiliation | Role |
|---|---|---|
| Magdy M Amin, Professor | Medical research ethics committee - Sohag university | Study Director |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jul 8, 2025 | |
| Reset | Jul 22, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jul 8, 2025 | Jul 22, 2025 |
| ID | Term |
|---|---|
| D041781 | Jaundice, Obstructive |
| ID | Term |
|---|---|
| D007565 | Jaundice |
| D006932 | Hyperbilirubinemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D049448 | Cholangiopancreatography, Magnetic Resonance |
| D014463 | Ultrasonography |
| D014057 | Tomography, X-Ray Computed |
| ID | Term |
|---|---|
| D008279 | Magnetic Resonance Imaging |
| D014054 | Tomography |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
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|
|
| D012877 | Skin Manifestations |
| D012816 | Signs and Symptoms |
| D003933 | Diagnosis |
| D003938 | Diagnostic Techniques, Digestive System |
| D007090 | Image Interpretation, Computer-Assisted |
| D011856 | Radiographic Image Enhancement |
| D007089 | Image Enhancement |
| D010781 | Photography |
| D011859 | Radiography |
| D014056 | Tomography, X-Ray |