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investigation of the impact of zinc level on the development of DM and to elaborate on whether daily consumption of zinc affects the disease's evolution.
The relationship between the pathophysiology of diabetes mellitus and trace element dysregulation emphasizes how crucial it is to maintain appropriate micronutrient status in order to manage this chronic metabolic disease. One promising strategy for enhancing glycemic control and lowering the risk of diabetic complications may be to address these underlying dietary imbalances.
Accordingly, the aim is to investigate the impact of zinc level on the development of DM and to elaborate on whether daily consumption of zinc affects the disease's evolution.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | haelthy volunteers | ||
| Type 2 DM patients | patients of Type 2 DM with no known complications |
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| Measure | Description | Time Frame |
|---|---|---|
| zinc serum level in the participnats | investigate the impact of zinc serum level on the development of DM | "through study completion, an average of 1 year" |
| Dietary micronutrient assessment using food questionnaire | Dietary micronutrient assessment using food questionnaire adopted from a questionnaire for screening the micronutrient intake of economically active South African adults | "through study completion, an average of 1 year" |
| Trace elements daily intake calculation | It will be calculated by multiplying the element contents measured in food (μg/kg) with the intake as estimated by the food micronutrient questionnaire (g/day). | "through study completion, an average of 1 year" |
| the dietary intake by kilogram (kg) of body weight (bw) | the dietary intake by kilograms (kg) of body weight (bw) by dividing by the weight of participants. | "through study completion, an average of 1 year" |
| Measure | Description | Time Frame |
|---|---|---|
| HbA1C mesurements | investigate the impact of serum zinc level on the glycemic control | "through study completion, an average of 1 year" |
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Inclusion Criteria:
Exclusion Criteria:
pregnancy and lactation type 1DM known DM complication other endocrinological disorders malignancy
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type 2 DM patients with no complication in comparison with health volunteers
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| Name | Affiliation | Role |
|---|---|---|
| sara eladwy, lecturer | Helioplis university | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University Hospitsl | Cairo | Egypt |
data will be assigned codes with no needs to share IPD
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| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| D004700 | Endocrine System Diseases |