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| Name | Class |
|---|---|
| Masih Daneshvari Hospital | OTHER |
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A Comparison of Ventilator Parameters (TV, DP, Total Mechanical Power, etc.) Between Successfully and unsuccessfully Weaned Patients with COPD Undergoing Mechanical Ventilation Due to Respiratory Failure, and Diagnosed with Pneumonia or ARDS in the Intensive Care Unit."
The objective of this study is to investigate which mechanical ventilation parameters and clinical findings influence weaning success by comparing successful and unsuccessful weaning patient groups among patients diagnosed with COPD who were intubated and monitored for more than five days in the intensive care unit. The findings of this study may contribute to the development of future treatment protocols and criteria for evaluating the weaning process.
This study is planned to be conducted in two centers: Bakırköy Dr. Sadi Konuk Training and Research Hospital in Istanbul and Shahid Beheshti University of Medical Sciences, Masih Daneshvari Hospital in Tehran. This multicenter study aims to facilitate the comparison of data obtained under different geographical and clinical conditions, thereby enabling a broader analysis of factors influencing the weaning process across a larger patient population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Weaned | patients with successful weaning from mechanic ventilator | ||
| Non-weaned | patients who have failed to wean from ventilator |
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| Measure | Description | Time Frame |
|---|---|---|
| Successful Weaning | The primary outcome of this study will be the successful weaning from mechanical ventilation. This will be defined as the patient being successfully extubated and maintaining adequate oxygenation for more than 48 hours without requiring reintubation or mechanical ventilation support. | 48 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Mechanical Ventilator Parameters | A comparison of total mechanical power between the weaned and non-weaned patient groups. | 48 hours |
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Inclusion Criteria:
Exclusion Criteria:
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Intubated patients with COPD which has been diagnosed Pneumonia or ARDS and have admission to icu and stayed for more than 5 years.
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| Name | Affiliation | Role |
|---|---|---|
| Zafer Cukurova, M.D | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | Study Chair |
| Seyed Mohammadreza Hashemian, M.D | Masih Daneshvari Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bakirkoy Dr Sadi Konuk Research and Training Hospital | Istanbul | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D055371 | Acute Lung Injury |
| D011014 | Pneumonia |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D055370 | Lung Injury |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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