Changes in FeNO Value During Pulmonary Rehabilitation in Patients with Asthma

Change in Daily FeNO During Three Weeks of Inpatient Pulmonary Rehabilitation in Patients with Asthma

This study investigates the use of fractional exhaled nitric oxide (FeNO) measurement to monitor non-pharmacological therapy during a three-week inpatient rehabilitation programme for asthma patients. It compares FeNO levels (measured three times a day) with clinical parameters and quality of life to analyse daily fluctuations and the acute effect of exercise training on FeNO levels. As FeNO is a non-invasive biomarker of airway inflammation, this study aims to expand its role in therapy monitoring and explore its application in a rehabilitation setting.

Inclusion Criteria:

• confirmed diagnosis of bronchial asthma (all disease severities)
• Chronic Obstructive Pulmonary Disease (COPD) with an asthma component, where the asthma component plays a clinically relevant role
• written informed consent

Exclusion Criteria:

• Chronic Obstructive Pulmonary Disease (COPD) as the primary disease
• unability to perform FeNO measurement independently