To assess procedural success and short term clinical outcomes of primary PCI to isolated LCx acute occlusion.

ST-segment elevation myocardial infarction (STEMI) involving acute occlusion of the left circumflex (LCx) coronary artery represent only 14-21% of STEMIs

LCx acute occlusion may be difficult to be diagnosed . Only 50% of patients with LCx occlusion exhibited ST segment elevation during the acute phase, 38% showed no ST segment changes, while 15% presented with isolated ST segment depression This may lead to delay in transfer to cath lab, delay in reperfusion therapy and consequently loss of more myocytes and more major adverse cardiovascular events (MACE) .

Due to relative rare occurrence of isolated LCx coronary artery occlusion, little is known in literature about the clinical outcomes of isolated LCx occlusion , so we will conduct a retrospective observational study in our tertiary primary percutaneous coronary intervention (PCI) center to detect the incidence , procedural and clinical outcomes after 6 months of patients who had isolated LCx acute occlusion and underwent primary PCI.

Inclusion Criteria:

• Patients presented to Assiut University heart hospital with STEMI who underwent primary PCI that revealed isolated LCx acute occlusion (single culprit artery) between January 2018 to January 2025 will be included.

Exclusion Criteria:

-Patients with cardiogenic shock, NYHA class III-IV and multivessel coronary artery disease will be excluded.

Baseline demographic, angiographic and clinical data, including cardiovascular risk factors, will be retrospectively collected. For follow up, we will contact every patient included in our study to ask about MACE.