Evaluation of the repeatability and reproducibility of ADC maps in both primary and non-primary lesions lymph nodes in patients with head and neck cancer, using an acquisition protocol Standardized DWI

DWI imaging consists of a spin-echo echo-planar sequence (SE-EPI) that will be acquired with 1.5 T or 3 T tomographs according to the equipment of the individual centers involved, setting the acquisition parameters after the administration of any contrast medium.

Inclusion Criteria:

• age over 18 years;
• primary squamous cell carcinoma (SCC) of the hypopharynx, oropharynx, or oral cavity; confirmed by histology;
• a lesion visible on at least three consecutive DWI images, with a minimum diameter of 2 cm;
• specific written informed consent;

Exclusion Criteria:

• incomplete acquisition of DWI images;
• presence of artifacts that do not allow quantitative analysis of DWI images;
• performance status 2 or more according to Zubrod.

Patients with SCC of the head and neck who, according to standard procedures, will have to undergo an MRI examination fordiagnostic purposes.

Patients must also meet the inclusion criteria