Effects of Intrathecal Midazolam (1mg) With Hyperbaric Bupivacaine 0.5% (15mg) for Spinal Anesthesia for C-section

Effects of Intrathecal Midazolam (1mg) With Hyperbaric Bupivacaine 0.5% (15mg) for Spinal Anesthesia for Caesarean Section

This study evaluates the effects of intrathecal midazolam (1 mg) combined with hyperbaric bupivacaine 0.5% (15 mg) for spinal anesthesia in cesarean section patients.

The addition of midazolam, a benzodiazepine with analgesic and anxiolytic properties to bupivacaine is hypothesized to enhance the quality of anesthesia and postoperative pain relief without significant side effects. A comparative analysis was conducted to assess sensory and motor block characteristics, postoperative analgesia duration, maternal hemodynamic stability, and neonatal outcomes.

Inclusion Criteria:

• Female patients presented for elective cesarean section.
• All ASA I & II patients .
• Age between 18 to 35 years.

Exclusion Criteria:

• Contraindication to spinal anesthesia.
• Patient not willing or previous bad experience with it.
• All ASA III & IV class was excluded from the study.
• Patients with documented bleeding disorders i.e. low platelet count, deranged PT/APTT/INR, DIC etc.
• Hypertensive patients
• Patients with Diabetes mellitus.
• Obese patients BMI >30.
• PIH (pre- eclampsia and eclapmsia)"