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Brief Summary:
This study aims to compare the efficacy of short-duration (240 sec) and long-duration (480 sec) pulsed radiofrequency (PRF) applications on pain, functionality, patient satisfaction, and side effect profiles in patients with lumbosacral radicular pain. The PRF procedure will be applied to the dorsal root ganglion (DRG) under fluoroscopic guidance.
In this study, all procedures will be performed in the prone position under sterile conditions and guided by fluoroscopy. After identifying anatomical landmarks, the cannula will be positioned close to the dorsal root ganglion. The tip of the cannula will be placed in the dorsal-cranial quadrant of the intervertebral foramen in the lateral view, and between one-third and halfway along the pedicle column in the anteroposterior view. Once the RF cannula is properly positioned, an RF electrode will be inserted through the cannula and connected to the RF generator. The final position of the RF cannula will be confirmed by sensory stimulation (paresthesia) at less than 0.5 V and motor stimulation perceived at a level at least 1.5 times greater than the sensory stimulation threshold.
In the short-duration PRF group, a PRF cycle will be applied at 42°C for 240 seconds, while in the long-duration group, it will be applied at 42°C for 480 seconds. Following the PRF application, epidural spread will be confirmed using contrast dye, after which 4 mL of a solution containing 8 mg dexamethasone and 5 mg bupivacaine will be injected at each level.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients with lumbosacral radicular pain | patients with lumbosacral radicular pain resistant to conservative treatments |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| The duration of the intervention will be 240 seconds | Procedure | Dorsal Root Ganglion pulsed radiofrequency 240sec |
|
| Measure | Description | Time Frame |
|---|---|---|
| Numeric rating scale on pain severity (0 = no pain, 10 = unbearable pain)) | Change in pain severity | 1, 3, and 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Global perceived effect (GPE) | Change in GPE scores according to the 7-point Likert scale (1=worst, 7=best) over time will be used to assess patient satisfaction and improvement | 1, 3, and 6 months |
| Oswetry disability index (ODI) |
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Inclusion Criteria:
Age ≥ 18 years
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Patients to undergo DRG PRF for lumbar radicular pain in bilkent city hospital algology clinic
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ankara Bilkent City Hospital Pain Medicine | Ankara | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31337167 | Result | Wan C, Dong DS, Song T. High-Voltage, Long-Duration Pulsed Radiofrequency on Gasserian Ganglion Improves Acute/Subacute Zoster-Related Trigeminal Neuralgia: A Randomized, Double-Blinded, Controlled Trial. Pain Physician. 2019 Jul;22(4):361-368. |
| Label | URL |
|---|---|
| Related Info | View source |
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| Dorsal Root Ganglion pulsed radiofrequency 480sec | Procedure | The duration of the intervention will be 480 seconds |
|
Change in 10-item Oswestry disability index (ODI) questionnaire (range: 0-100; 0 = no disablility) over time will be used to assess physical function
| 0, 1, 3, and 6 months |
| Patient satisfaction | Change in Patient satisfaction (5-point Likert scale, 0= very disappointed, 5=very satisfied) over time will be used | 1, 3, and 6 months |
| Change in analgesic use | Change in analgesic use over time (0=same, 1=decreased, 2=increased) | 1, 3, and 6 months |