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| Name | Class |
|---|---|
| Yiwu Fuyuan Private Hospital | UNKNOWN |
| Hangzhou Xiaoshan Traditional Chinese Orthopedic Hospital | UNKNOWN |
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The goal of this clinical trial is to learn if vitamin D supplementation affects postoperative rehabilitation in osteoarthritis patients who underwent joint arthroplasty. The main questions it aims to answer are:
Does oral vitamin D supplementation for a period of time after joint arthroplasty affect the postoperative recovery speed in patients who have vitamin D deficiency? Does oral vitamin D supplementation after joint arthroplasty affect the long-term recovery of joint functions in patients who have vitamin D deficiency?
Participants will:
Take vitamin D oral supplement every day for 3 months. Visit the clinic in 1, 3, 6, 12 months after joint replacement surgery for checkups and tests.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vitamin D oral supplement | Experimental | Using vitamin D oral supplement that has been widely used in clinic |
|
| No vitamin D supplementation | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vitamin D | Drug | Vitamin D oral supplementation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Knee joint function | Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Pain ranging from 0 to 20 points; stiffness, 0 to 8 points; and physical function, 0 to 68 points. Higher scores represent worse pain, stiffness, and functional limitations. | From enrollment to the end of treatment at 1 year |
| Hip joint function | Harris Hip Score. The maximum score possible is 100. Results can be interpreted with the following: <70 = poor result; 70-80 = fair, 80-90 = good, and 90-100 = excellent. | From enrollment to the end of treatment at 1 year |
| Muscle strength | Using portable muscle strength tester to measure flexor and extensor muscle strength of knee or hip joint | From enrollment to the end of treatment at 1 year |
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Inclusion Criteria:
Exclusion Criteria:
1. Having other diseases that could cause damage to the bone or cartilage structure of the hip or knee, such as trauma, joint infection, congenital joint malformation, and systemic diseases such as rheumatoid arthritis and gout.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xiang Zhao, MD | Contact | 8613750835297 | flyingzhao@zju.edu.cn | |
| Zihao Qu, MD | Contact | 8615700079560 | qu_z.h@zju.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Xiang Zhao, MD | 2nd Affiliated Hospital, School of Medicine, Zhejiang University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| 2nd Affiliated Hospital, School of Medicine, Zhejiang University | Hangzhou | Zhejiang | China |
IPD cannot be shared publicly due to the sponsor policy.
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| ID | Term |
|---|---|
| D015207 | Osteoarthritis, Hip |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| ID | Term |
|---|---|
| D014807 | Vitamin D |
| ID | Term |
|---|---|
| D012632 | Secosteroids |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
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