Comparative Efficacy of Buprenorphine Transdermal Patch Versus Tramadol in Postoperative Analgesia for Shoulder Arthroscopy

Comparative Efficacy of Buprenorphine Transdermal Patch Versus Tramadol in Postoperative Analgesia for Shoulder Arthroscopy: a Randomized Controlled Trial.

This study compares the efficacy, safety, and patient satisfaction of the Buprenorphine 10 mg transdermal patch versus Tramadol for postoperative analgesia in shoulder arthroscopic surgery. The study hypothesizes that Buprenorphine provides superior pain relief with fewer side effects compared to Tramadol.

Inclusion Criteria:

• Adults aged 18 to 65 years.
• Patients undergoing elective shoulder arthroscopy.
• Classified as ASA (American Society of Anesthesiologists) physical status I or II.
• Able to provide informed consent.
• Willing to comply with study protocols and follow-up assessments

Exclusion Criteria:

• Known allergy or hypersensitivity to Buprenorphine, Tramadol, or any related compounds.
• History of substance abuse, opioid dependency, or chronic pain requiring ongoing analgesic therapy.
• Pregnant or breastfeeding individuals.
• Presence of severe hepatic, renal, or respiratory disease.
• Any psychiatric or neurological condition that might interfere with pain perception or reporting (e.g., dementia, severe anxiety).
• Participation in another clinical trial within the last 30 days.
• Inability to apply or tolerate a transdermal patch (e.g., due to skin disorders or sensitivities).
• Contraindications to interscalene brachial plexus block, such as infection at the site, coagulopathy, or pre-existing neuropathy in the upper limb.