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| Name | Class |
|---|---|
| Stiftung Vinetum | UNKNOWN |
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The BEready project aims to find out how people in the Canton of Bern can be helped to be more prepared for the next pandemic. BEready wants to understand how infections spread among people as well as between people and animals. BEready wants to find out how social and environmental factors can influence the transmission or catching of infectious diseases. BEready wants to better understand how households and their pets in the Canton of Bern were and continue to be affected by the coronavirus disease 2019 (COVID-19).
The overall aim is to establish BEready as a 'pandemic preparedness cohort', a cohort with a well-characterised study population of households, which has an infrastructure to conduct studies about infectious diseases, and which can be rapidly mobilised to respond to a new pandemic. BEready aims to understand the epidemiology and transmission of infectious diseases (particularly viral respiratory pathogens) in households including pets in the canton of Bern, and to engage diverse communities in efforts to strengthen pandemic preparedness.
The objectives are:
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| Measure | Description | Time Frame |
|---|---|---|
| Response rate among the randomly sampled participants | Percentage agreeing to take part, divided by the number invited, by age and sex (study level) | Baseline |
| Attendance of follow up visits (to derive factors associated with research participation) | Percentage of completed questionnaire (study level) | At every annual follow-up for up to 100 years |
| Incidence of respiratory virus detection in symptomatic persons | Test positivity: percentage of nasal swab samples with a positive result for specific respiratory viruses among all viruses detected amongst those reporting disease events cumulatively by the end of one year; incidence rate for any detected virus and for specific viruses: number of nasal swab samples with a positive result per 100 person years of follow-up (individual level, infection-related) | At the end of a 12 months period |
| Seroprevalence of antibodies to respiratory viruses | Proportion of serum samples with antibodies to specific respiratory viruses (individual level, infection-related) | At baseline and annually thereafter for up to 100 years |
| Incidence of co-infection/co-colonisation at the pet/owner interface | Proportion of serum samples with antibodies to specific parasites (individual level, infection-related) | Throughout follow-up for up to 100 years |
| Incidence of animal diseases diagnosed through syndromic surveillance | Based on each case definition, e.g. febrile illness, incidence of syndromic diagnoses by month (individual level, infection-related) |
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Inclusion criteria for adults and children:
Inclusion criteria for household pets: Pets of eligible household members with the consent of their owners.
Exclusion criteria for adults and children: Currently planned move outside the canton of Bern
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BEready will include a spectrum of the Bernese population living in private households, including adults, children and pets. A private household is defined as a person living alone or group of persons living in the same dwelling.
The study population for the BEready cohort will be enrolled from different sources in the source population of the canton of Bern. BEready aims to enrol around 1,500 households in total from:
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| Name | Affiliation | Role |
|---|---|---|
| Nicola Low, Prof. Dr. med. | University of Bern | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Bern | Bern | 3012 | Switzerland |
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| Label | URL |
|---|---|
| BEready Cohort study website | View source |
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Upon request
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D007239 | Infections |
| D015047 | Zoonoses |
| D012141 | Respiratory Tract Infections |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
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Blood, nasal swabs
| Throughout follow-up for up to 100 years |
| Prevalence of post-acute viral symptoms | Individual level, infection-related | At baseline and annually thereafter for up to 100 years |
| Gender roles | Gender is a cross-cutting theme. Associations with gender measured by questionnaire will be examined for all endpoints (individual level, personal, social, demographic). | At all timepoints for up to 100 years |
| Number of daily social contacts | Numbers of social contacts between humans, according to age group and location (individual level, personal, social, demographic) | At baseline and annually thereafter for up to 100 years |
| Affective polarisation | Mean and standard deviation of Likert scale scores (individual level, personal, social, demographic) | At baseline |
| Knowledge of pandemic preparedness | Knowledge measured by questionnaire. Summary of the survey data (individual level, personal, social, demographic) | At baseline |
| Knowledge of vector-borne diseases | Knowledge measured by questionnaire. Summary of the survey data (individual level, personal, social, demographic) | At baseline |
| Experienced marginalisation | Experience measured by questionnaire. Summary of the survey data (individual level, personal, social, demographic) | At baseline |
| D003333 |
| Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D000820 | Animal Diseases |