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This retrospective cohort study was designed to explore the relationship between blood pressure and cognitive impairment after stroke
Patients who have been followed up for more than 3 months after stroke will be included in the study. Basic data of patients and factors that may be related to cognitive impairment will be collected, and the relationship between blood pressure and cognitive impairment after stroke will be explored by univariate regression analysis and multivariate regression analysis. Univariate logistic regression model and multivariate logistic regression model were used to explore the relationship between blood pressure level and the risk of cognitive impairment after stroke, and the effect of blood pressure level and cognitive impairment sub-line in different patients was evaluated by subgroup analysis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| NPSCI | NPSCI was defined as a score of MMSE≥26. | ||
| PSCI | The prime outcome PSCI was defined as the cognitive impairment occurred after stroke and was still present three months after stroke and cognitive impairment was defined as a score of MMSE<26. |
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| Measure | Description | Time Frame |
|---|---|---|
| Mental State Examination Scale (MMSE) | Global cognitive function assessment. Easy to use and one of the most used scales to screen person with cognitive impairment in the world. The minimum and maximum values range from 0 to 30. Higher score means better cognition level. | Mini-Mental State Examination (MMSE) assessment will be completeed at 3 monthes after stroke |
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Inclusion criteria:
Exclusion criteria:
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Stroke patients admitted to the First Branch of the First Affiliated Hospital of Chongqing Medical University between 2022 and 2024 were retrospectively reviewed.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dingqun Bai | Contact | 13808380876 | baidingqun@hospital.cqmu.edu.cn | |
| Defei Chen | Contact | +8615188017034 | 2283273437@qq.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| First Affiliated Hospital of Chongqing Medical University | Recruiting | Chongqing | Chongqing Municipality | China |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |