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assessment the Improvement symptoms of obstructed defecation after biofeedback training versus botulinum toxin injection
This is a randomized controlled trial including 78 patients diagnosed with obstructed defecation syndrome confirmed by detailed history talking, full clinical examination, anorectal manometry and defecography.
Included patients divided into two equal groups: first group ( biofeedback therapy group) patients recieved biofeedback therapy for six sessions over one month, the second group:( botulinum toxin group) received botulinum toxin injection 100 IU in buborectalis muscle.
The primary outcome is improvement of symptoms after one year
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Biofeedback therapy group | Active Comparator | Patients with dyssynergic defecation underwent biofeedback training program in the form of six sessions over one month |
|
| Botox injection group | Active Comparator | Participants in this group received 100 international unit of botulinum toxin type A that was injected injections into the puborectalis muscle to alleviate dyssynergic defecation by reducing muscle overactivity and improving coordination. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Biofeedback therapy | Device | Biofeedback therapy involves the use of specialized equipment to provide real-time feedback on pelvic floor muscle activity. Participants are trained to improve muscle coordination and relaxation through guided exercises, targeting the resolution of dyssynergic defecation. |
| Measure | Description | Time Frame |
|---|---|---|
| Improvement of symptoms of constipation for one year follow up |
| One year |
| Measure | Description | Time Frame |
|---|---|---|
| Improvement of pain for one year follow up | Pain improvement on the visual analogue scale is from 0 to 10, where 0 means no pain and 10 means the worst pain. | One year |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mansoura faculty of medicine | Al Mansurah | 35516 | Egypt |
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| ID | Term |
|---|---|
| D001676 | Biofeedback, Psychology |
| D019274 | Botulinum Toxins, Type A |
| ID | Term |
|---|---|
| D026441 | Mind-Body Therapies |
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D001521 | Behavior Therapy |
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|
| Botulinum Toxin A (Botox ) | Drug | Botulinum toxin is injected into the pelvic floor muscles to reduce muscle overactivity and improve coordination, aiming to relieve symptoms of dyssynergic defecation. |
|
| D011613 |
| Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
| D030141 | Feedback, Psychological |
| D001905 | Botulinum Toxins |
| D008666 | Metalloendopeptidases |
| D010450 | Endopeptidases |
| D010447 | Peptide Hydrolases |
| D006867 | Hydrolases |
| D004798 | Enzymes |
| D045762 | Enzymes and Coenzymes |
| D045726 | Metalloproteases |
| D001426 | Bacterial Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D001427 | Bacterial Toxins |
| D014118 | Toxins, Biological |
| D001685 | Biological Factors |