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The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later). The main question[s] it aims to answer are:
Does light therapy reduce OCD symptoms? Does light therapy advance the circadian clock? If there is a comparison group: Researchers will compare a higher dose of light therapy to a lower dose to see if dose amount affects symptom reduction.
Participants will asked to:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Higher dose | Experimental | Participants will be given wearable light therapy devices that emit a higher light intensity. |
|
| Lower dose | Sham Comparator | Participants will be given wearable light therapy devices that emit a lower light intensity. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Light therapy | Behavioral | 5 weeks of light therapy administered via wearable light therapy glasses worn for 1 hour each morning after awakening. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Yale Brown Obsessive-Compulsive Scale (YBOCS) | A retrospective clinical interview of OCD symptom severity. Score range from 0 to 40 and higher scores indicate more severe OCD symptoms. | Administered at baseline, in treatment week 3, and post-treatment (3 administrations over 7 weeks) |
| Daily Perseverative Thinking Questionnaire | Self-report measure of momentary transdiagnostic repetitive negative thinking. Score range from 6 to 42 and higher scores indicate more severe repetitive negative thinking. | Administered 4 times/day for 2 weeks at baseline, 4 times/day for 1 week in treatment week 3, and 4 times/day for 1 week in treatment week 5 |
| Measure | Description | Time Frame |
|---|---|---|
| Circadian melatonin phase | Dim light melatonin onset assessed by taking hourly saliva samples in dim light conditions for 10 hours beginning 7 hours before typical bedtime and ending 2 hours after typical bedtime. | At baseline and post-treatment (after 5 weeks of treament) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Rebecca Cox, BA | Contact | 314-935-8111 | scraplab@wustl.edu |
| Name | Affiliation | Role |
|---|---|---|
| Rebecca Cox, PhD | Washington University School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Washington University | Recruiting | St Louis | Missouri | 63130 | United States |
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| ID | Term |
|---|---|
| D003193 | Compulsive Personality Disorder |
| ID | Term |
|---|---|
| D010554 | Personality Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D010789 | Phototherapy |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
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