Probiotics Combined with Enteral Nutrition Reduces Postoperative Infectious Complications in PD

Probiotics Combined with Enteral Nutrition on Infectious Complications After Pancreaticoduodenectomy:a Single-centre, Prospective Randomised, Open, Parallel-controlled, Superiority Study

Probiotics combined with enteral nutrition reduces postoperative infectious complications in PD

Inclusion Criteria:

• Adult patients greater than 18 years of age;
• Indication for elective pancreaticoduodenal surgery;
• Patients who understand the nature of the trial and are willing and able to provide written consent

Exclusion Criteria:

. Current or recent (within the previous 1 month) use of probiotic-based products or antibiotic therapy medications.

Inability to tolerate PD due to cardiopulmonary function and other parameters

• Received radiotherapy before surgery
• Emergency PD surgery
• Pregnant and breastfeeding women