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Metabolic dysfunction asociated steatotic liver disease prevalence is 25%world wide diabetic patients have a risk for MASLD then have hepatic fibrosis so we study correlation Between Serum Adiponectin And Resistin Levels And Degree of Hepatic fibrosis In Metabolic dysfunction asociated steatotic liver disease in patients with type2 Diabetes Mellitus
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MASLD patients with hepatic fibrosis | MASLD with hepatic fibrosis with type 2 diabetes mellitus |
| |
| MASLD without hepatic fibrosis | MASLD with out hepatic fibrosis with type 2 diabetes mellutis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| serum Adiponectine and Resistin | Diagnostic Test | corrolation between serum adiponectin and Resistin levels and degree of hepatic fibrosis |
|
| Measure | Description | Time Frame |
|---|---|---|
| degree of hepatic fibrosis in MASLD with type 2 diabetes mellitus | adiponectineand resistine level with degree of hepatic fibrosis in MASLD pt. with type 2 DM | 1 year |
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Inclusion Criteria:
Exclusion Criteria:alcholics ,chronic liver disease elevated liver functions , sever infection
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MASLD patients with hepatic fibrosis groupA,MASLD patients without hepatic fibrosis
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| ELZAHRAA K Mohammed, spcialist | Contact | 01064954825 | elzahraaadbelrehem@sohag.edu.eg | |
| usama M Abdelaal, professor | Contact | 01065962094 |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37700494 | Background | Chan WK, Chuah KH, Rajaram RB, Lim LL, Ratnasingam J, Vethakkan SR. Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A State-of-the-Art Review. J Obes Metab Syndr. 2023 Sep 30;32(3):197-213. doi: 10.7570/jomes23052. Epub 2023 Sep 13. | |
| 38278621 | Background | Marchesini G, Vettor R, Pinzani M. MASLD emerging from the fog of fatty liver. J Hepatol. 2024 Feb;80(2):178-180. doi: 10.1016/j.jhep.2023.10.011. Epub 2023 Nov 30. No abstract available. |
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| ID | Term |
|---|---|
| D008103 | Liver Cirrhosis |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D005355 | Fibrosis |
| D010335 | Pathologic Processes |
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| fibroscan | Diagnostic Test | hepatic fibrosis detection in type 2 diabetes mellutis |
|
| 36517002 | Background | Teng ML, Ng CH, Huang DQ, Chan KE, Tan DJ, Lim WH, Yang JD, Tan E, Muthiah MD. Global incidence and prevalence of nonalcoholic fatty liver disease. Clin Mol Hepatol. 2023 Feb;29(Suppl):S32-S42. doi: 10.3350/cmh.2022.0365. Epub 2022 Dec 14. |
| 28802062 | Background | Estes C, Razavi H, Loomba R, Younossi Z, Sanyal AJ. Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease. Hepatology. 2018 Jan;67(1):123-133. doi: 10.1002/hep.29466. Epub 2017 Dec 1. |
| D013568 |
| Pathological Conditions, Signs and Symptoms |