Neoadjuvant Radiotherapy Before Surgery for Rectal Cancer, Surgical and Oncological Outcome Analysis, Retrospective Case Control Study in a Single Institute.

Neoadjuvant Radiotherapy Before Surgery for Rectal Cancer, Surgical and Oncological Outcome Analysis, Retrospective Case Control Study in a Single Institute.

Pre-operative radiotherapy for clinical stage 3 rectal cancer outcome analysis, retrospective case-control study.

For clinical T3 rectal cancer, neo-adjuvant radiotherapy was proved to reduce local recurrent rate in the clinical trials. In this study, we analysis surgical and oncological outcomes of neo-adjuvant radiotherapy for stage 3 rectal cancer in the real world in a single institute and do further subgroups analysis as references for treatment plans.

Inclusion Criteria:

• Rectal cancer, clinical stage T3 or higher, with no distant metastasis.
• Age > =20 years, ASA class I-III.
• Underwent surgery.
• Complete medical records.

Exclusion Criteria:

• Non-rectal cancer.
• Clinical stage T1-T2.
• Stage IV with distant metastasis.
• Age < 20 years, ASA class IV-V.
• Incomplete medical records.
• HIV-positive patients (Human Immunodeficiency Virus).
• Patients who completed treatment after October 1, 2024.