The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery

The Effect of Preoperative Albumin Administration on Postoperative Acute Kidney Injury in Pediatric Patients With Hypoalbuminemia Undergoing Cardiac Surgery: A Prospective Randomized Clinical Trial

The study aims to evaluate whether preoperative albumin supplementation in pediatric patients with hypoalbuminemia undergoing cardiac surgery can reduce inflammatory responses and prevent acute kidney injury (AKI) following cardiopulmonary bypass.

Inclusion Criteria:

• Pediatric patients under 7 years of age undergoing cardiac surgery with cardiopulmonary bypass
• Preoperative serum albumin level of 4.0 g/dL or lower

Exclusion Criteria:

• abnormal preoperative creatinine level
• history of dialysis
• liver dysfunction
• diabetes
• history of hypersensitivity to albumin
• coagulation disorders