Classification of Adult-onset Diabetes in Five Subgroups in Pakistani Population

Classification of Adult-onset Diabetes in Five Subgroups in Pakistani Population

This study aims to classify adult-onset diabetes patients into distinct data-driven clusters, such as severe insulin-deficient, severe insulin-resistant, mild obesity-related, and mild age-related diabetes, based on clinical and biochemical characteristics. Using a cross-sectional design, data will be collected from individuals attending outpatient diabetes clinics at tertiary care hospitals in Pakistan. The study will analyze the distribution of metabolic and demographic characteristics within each cluster and assess subgroup-specific risks for diabetic complications. Additionally, the relationship between clustering variables and the risk of complications will be evaluated to enhance the understanding of diabetes heterogeneity and its impact on patient outcomes.

Inclusion Criteria:

• Patients of both genders whose age of disease onset was older than 16 years
• Patients newly diagnosed with or previously diagnosed with T2D
• Able and willing to provide written informed consent and to comply with the study

Exclusion Criteria:

• Patients with other medical comorbidities (not a complication of diabetes), such as malignancies.
• Pregnancy