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The purpose of this study is to assess the real-world effectiveness of deucravacitinib treatment in adults diagnosed with moderate-to-severe plaque psoriasis
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Participants that have initiated deucravacitinib treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Deucravacitinib | Drug | As prescribed by treating clinician |
|
| Measure | Description | Time Frame |
|---|---|---|
| Physician's Global Assessment (PGA) 0/1 response | Baseline and at months 4, 12, 18 (optional), and 24 | |
| Dermatology Life Quality Index (DLQI) 0/1 response | Baseline and at months 4, 12, 18 (optional), and 24 | |
| Time from date of treatment initiation to date of discontinuation | Up to 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in percentage involved Body Surface Area (BSA) from start of deucravacitinib treatment | Baseline and at months 4, 12, 18 (optional), and 24 | |
| Change in patient reported symptom burden as assed by the 100-point Visual Analog Scale (VAS) - Itch | Baseline and months 1, 4, 12, 18 (optional) and 24 |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients who have been diagnosed with moderate-to-severe plaque psoriasis and who intend to start deucravacitinib treatment in France
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| BMS Clinical Trials Contact Center www.BMSClinicalTrials.com | Contact | 855-907-3286 | Clinical.Trials@bms.com | |
| First line of the email MUST contain NCT # and Site #. | Contact |
| Name | Affiliation | Role |
|---|---|---|
| Bristol-Myers Squibb | Bristol-Myers Squibb | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chu Amiens Picardie - Site Sud | Recruiting | Amiens | 80054 | France |
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| Label | URL |
|---|---|
| BMS Clinical Trial Information | View source |
| FDA Safety Alerts and Recalls | View source |
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| Change in patient reported symptom burden as assed by the 100-point Visual Analog Scale (VAS) - Skin pain | Baseline and months 1, 4, 12, 18 (optional) and 24 |
| Change in patient reported symptom burden as assed by the 100-point Visual Analog Scale (VAS)] - Fatigue | Baseline and months 1, 4, 12, 18 (optional) and 24 |
| Physician's Global Assessment (PGA) score change from start of deucravacitinib treatment to follow-up | Baseline and at months 4, 12, 18 (optional), and 24 |
| Dermatology Life Quality Index (DLQI) score of ≤5 | Baseline and at months 1, 4, 12 18 (optional) and 24 |
| Body Surface Area (BSA) of ≤ 3% | Baseline and at months 4, 12, 18 (optional), and 24 |
| Body Surface Area (BSA) of ≤ 1% | Baseline and at months 4, 12, 18 (optional), and 24 |
| Reasons for deucravacitinib treatment discontinuation | Up to 24 months |
| Cabinet Médical Elisabeth Lion | Recruiting | Angers | 49100 | France |
|
| Ch Victor Dupouy | Recruiting | Argenteuil | 95107 | France |
|
| Local Institution - 089 | Completed | Argenteuil | 95107 | France |
| CH ARRAS | Recruiting | Arras | 62000 | France |
|
| Cabinet Dermatologie | Recruiting | Bordeaux | 33200 | France |
|
| Cabinet Dermatologie | Recruiting | Bordeaux | 33200 | France |
|
| Centre Hospitalier William Morey - Hématologie | Recruiting | Chalon-sur-Saône | 71100 | France |
|
| Local Institution - 053 | Completed | Clermont-Ferrand | 63000 | France |
| CHU Dijon | Recruiting | Dijon | 21000 | France |
|
| Local Institution - 077 | Not yet recruiting | Dijon | 21000 | France |
|
| CHU Grenoble Alps, Service de Dermatologie | Recruiting | La Tronche | 38700 | France |
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| Local Institution - 014 | Not yet recruiting | Le Mans | 72037 | France |
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| CH Emile Roux | Recruiting | Le Puy-en-Velay | 43000 | France |
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| Centre Hospitalier Lens | Recruiting | Lens | 62307 | France |
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| Centre de santé Filieris | Recruiting | Marcq-en-Barœul | 59700 | France |
|
| Hopital Saint Eloi | Recruiting | Montpellier | 34295 | France |
|
| Tagast 41 | Recruiting | Nice | 06000 | France |
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| Ch Georges Renon | Recruiting | Niort | 79021 | France |
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| Ch Georges Renon | Recruiting | Niort | 79021 | France |
|
| Hopital Caremeau | Recruiting | Nîmes | 30900 | France |
|
| Cabinet de dermatologie | Recruiting | Paris | 75012 | France |
|
| Local Institution - 086 | Completed | Paris | 75012 | France |
| Hôpital Privé Francheville | Recruiting | Périgueux | 24000 | France |
|
| Centre Hospitalier de Roubaix | Recruiting | Roubaix | 59056 | France |
|
| Centre Hospitalier de Roubaix | Recruiting | Roubaix | 59056 | France |
|
| Local Institution - 031 | Completed | Rouen | 76031 | France |
| Local Institution - 065 | Not yet recruiting | Saint-Germain-en-Laye | 78100 | France |
|
| Hia Begin | Recruiting | Saint-Mandé | 94163 | France |
|
| Centre Dermatologique | Recruiting | Saint-Maur-des-Fossés | 94100 | France |
|
| Hia Sainte Anne | Recruiting | Toulon | 83800 | France |
|
| Hia Sainte Anne | Recruiting | Toulon | 83800 | France |
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| Hopital Larrey | Recruiting | Toulouse | 31059 | France |
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| Hopital Larrey | Recruiting | Toulouse | 31059 | France |
|
| Hopital Larrey | Recruiting | Toulouse | 31059 | France |
|
| Hopitaux de Brabois | Recruiting | Vandœuvre-lès-Nancy | 54511 | France |
|
| Hopitaux de Brabois | Recruiting | Vandœuvre-lès-Nancy | 54511 | France |
|
| Médipôle Hôpital Mutualiste | Recruiting | Villeurbanne | 69100 | France |
|
| Médipôle Hôpital Mutualiste | Recruiting | Villeurbanne | 69100 | France |
|
| Cabinet Medical | Recruiting | La Chaux-de-Fonds | 2300 | Switzerland |
|
| Cabinet Medical | Recruiting | La Chaux-de-Fonds | 2300 | Switzerland |
|
| Cabinet Medical | Recruiting | La Chaux-de-Fonds | 2300 | Switzerland |
|
| Cabinet Medical | Recruiting | La Chaux-de-Fonds | 2300 | Switzerland |
|
| Cabinet Medical | Recruiting | La Chaux-de-Fonds | 2300 | Switzerland |
|
| Cabinet Medical | Recruiting | La Chaux-de-Fonds | 2300 | Switzerland |
|
| Cabinet Medical | Recruiting | La Chaux-de-Fonds | 2300 | Switzerland |
|
| Local Institution - 056 | Completed | La Chaux-de-Fonds | 2300 | Switzerland |
| Local Institution - 059 | Completed | La Chaux-de-Fonds | 2300 | Switzerland |
| ID | Term |
|---|---|
| D011565 | Psoriasis |
| ID | Term |
|---|---|
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| C000628674 | deucravacitinib |
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