Clinical Efficacy of In-office Bleaching With Different Concentrations of Hydrogen Peroxide

Clinical Evaluation of In-office Bleaching With Low, Medium, and High Concentrate Hydrogen Peroxide: A 6-month a Double-blinded Randomized Controlled Trial

Objective: The study evaluated the longevity, effectiveness, sensitivity and impact on the oral health-related quality of life of in-office dental bleaching using low, medium, and high concentrate hydrogen peroxide.

Material and Methods: Randomized, parallel, and double-blinded clinical trial was performed with 54 participants using18% hydrogen peroxide (HP), 20%HP, and 40%HP in-office bleaching agent. Tooth color was evaluated at baseline, after the 1st session bleaching, after the 2st session bleaching and 6 months (T5) after finishing the bleaching using spectrophotometer. Tooth sensitivity was measured with the Visual Analog Scale at baseline, immediately after bleaching, after 1 day, and after 7 days. The impact on quality of life was evaluated using the Oral Health Impact Profile (OHIP) questionnaire at baseline, and 6 months after bleaching.

Inclusion Criteria:

• Women and men (at least 18 years old)
• People with good oral and general health
• People without periodontal disease
• Teeth without caries
• Teeth A3 or darker according to the VITA Easy Shade Guide (VITA Zanhnfabrik, BadSckingrn, Germany)

Exclusion Criteria:

• Having undergone teeth bleaching procedure in the last 2 years,
• People with tooth sensitivity,
• Use of fixed orthodontic appliances or prostheses on upper and/or lower anterior teeth,
• People with gingival recession,
• Discoloration due to parafunction, tetracycline or fluorosis,
• Smokers,
• Tooth fracture.