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| Name | Class |
|---|---|
| Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | OTHER |
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This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group | Experimental | EIT-guided Phigh settings during APRV |
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| Control group | No Intervention | Pplat-guided Phigh settings during APRV |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EIT-guided Phigh settings during APRV | Device | The Phigh level selected for the patients in the Intervention group was the intercept point of cumulated collapse and overdistension percentage curves, providing the best compromise between collapsed and overdistended lung. |
| Measure | Description | Time Frame |
|---|---|---|
| The effects of Phigh guided by different methods on regional lung ventilation assessed by EIT | 1 Hour Post-Intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Global inhomogeneity assessed by electrical impedance tomography | 1 Hour Post-Intervention | |
| Center of ventilation assessed by electrical impedance tomography | 1 Hour Post-Intervention | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| jing Xiao Zou | Contact | +862785351606 | 249126734@qq.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wuhan Union hospital | Recruiting | Wuhan | Hubei | 237000 | China |
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| ID | Term |
|---|---|
| D055371 | Acute Lung Injury |
| ID | Term |
|---|---|
| D055370 | Lung Injury |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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| ventilation/perfusion matching assessed by EIT |
| 1 Hour Post-Intervention |
| Respiratory system compliance | Tidal volume divided by plateau pressure | 1 Hour Post-Intervention |
| mean arterial pressure | 1 Hour Post-Intervention |