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| Name | Class |
|---|---|
| Icadom | INDUSTRY |
| Centre de Recherche en Nutrition Humaine Rhone-Alpe | OTHER |
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To better understand how diet influences health during aging, the French National Research Institute for Agriculture, Food and the Environment (INRAE) is working with the Gérontopôle Auvergne-Rhône-Alpes on a project called Part'AGE. Part'AGE is a participatory research project where researchers want to recruit 1,000 people aged between 55 and 75 years, men and women, living in Auvergne-Rhône-Alpes in urban or rural areas. The goal is to study eating habits and state of health. To do this, researchers will examine many factors that can influence them, such as physical activity, overall health, consumption patterns or territories. Researchers will collect detailed information to classify participants into different groups (food typologies) based on their eating habits and state of health. With this distribution, the goal is to be able to give each group personalized nutritional advice to age in better health.
To participate in the study, the participants will need to collect a few drops of blood from the end of the finger, a urine sample, and do some tests (mobility, oral health). It will also be necessary to fill out questionnaires on eating habits, physical activity, and other aspects that may influence health. The benefices for to participants will be to contribute to nutrition research and to receive personalized feedback and advices on eating habits.
The main objective of the study is to characterize the food consumption profile of a population of people aged 55 to 75, men and women, living in the Auvergne-Rhône-Alpes region, either in an urban or rural environment. The aim is to classify volunteers into dietary typologies associated with more or less successful aging. Thus, the investigators will classify volunteers into five dietary typologies:
For each of these dietary typologies, the investigators will explore the diversity of: cardio-metabolic capacities; diet; mobility; health status (oral health, intestinal health, stress, fatigue, anxiety, sleep, addictions); the psychological-socio-economic dimension; biological parameters obtained after the collection of biological samples.
This study will be entirely carried out by correspondence, without the volunteers needing to travel. Wide communication on the study will first be carried out in Auvergne-Rhône-Alpes. A phone number and an email address of the research team will be left for people wishing more information. Volunteers will directly contact the administrative agent in charge of selection in order to leave their contact details. The administrative agent will respond or contact the participants in return to present the study in its entirety, tell them about their rights, and check their eligibility. If they are eligible and interested, volunteers will be sent the information form and a connection guide by email or by post and an appointment will be scheduled for a dematerialized inclusion visit with a study investigator. The inclusion visit will be carried out remotely, from a secure platform. Upon receipt of consent, the investigators will assign an identification number to the volunteer and will trigger the sending by post of a phenotyping BOX to their home containing all the material necessary to carry out the study, accompanied by an explanatory note. The volunteers will connect to a secure platform to complete 29 questionnaires, will carry out functional tests and anthropometric measurements and will collect their biological samples (blood drops and urine). Volunteers will send their biological samples to the INRAE laboratory within 2 days of their collection.
In return, volunteers will have the opportunity to:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| survey on eating behavior, physical activity and health status | Other | Participatory research: participants will carry out surveys, functional tests and urine and blood sampling completely independently |
| Measure | Description | Time Frame |
|---|---|---|
| Classification of our study population into 5 dietary typologies associated with more or less successful aging |
| From enrollment to the end of the surveys at 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Blood parameters and waist-to-hip ratio | Assessment of glucose, C-peptide, triglycerides, cholesterol, amino acids, prealbumin and CRP levels in fingertip blood collected at home, and waist-to-hip ratio. | From enrollment to the end of the surveys at 30 day |
| Assessment of dietary habits and choices |
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Inclusion Criteria:
Exclusion Criteria:
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Participants will be recruited from the Auvergne-Rhône-Alpes region, taking care to recruit both urban and rural people.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sergio Polakof, Ph D | Contact | +33 4 73 62 48 95 | sergio.polakof@inrae.fr | |
| Laurent Mosoni, Ph D | Contact | +33 4 73 62 48 27 | laurent.mosoni@inrae.fr |
| Name | Affiliation | Role |
|---|---|---|
| Clement Lahaye, MD, Ph D | Unité mobile de Gériatrie - Centre Hospitalier Universitaire- Site Gabriel Montpied | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ICADOM | Not yet recruiting | Meylan | Isere | 38240 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28829397 | Background | de Toro-Martin J, Arsenault BJ, Despres JP, Vohl MC. Precision Nutrition: A Review of Personalized Nutritional Approaches for the Prevention and Management of Metabolic Syndrome. Nutrients. 2017 Aug 22;9(8):913. doi: 10.3390/nu9080913. | |
| 32528151 | Background | Berry SE, Valdes AM, Drew DA, Asnicar F, Mazidi M, Wolf J, Capdevila J, Hadjigeorgiou G, Davies R, Al Khatib H, Bonnett C, Ganesh S, Bakker E, Hart D, Mangino M, Merino J, Linenberg I, Wyatt P, Ordovas JM, Gardner CD, Delahanty LM, Chan AT, Segata N, Franks PW, Spector TD. Human postprandial responses to food and potential for precision nutrition. Nat Med. 2020 Jun;26(6):964-973. doi: 10.1038/s41591-020-0934-0. Epub 2020 Jun 11. |
| Label | URL |
|---|---|
| Project web site | View source |
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As soon as possible, results will be published. Upon requests, sharing of data could be considered on a case-by-case basis.
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Dried whole blood; Urine.
Assessment of dietary habits and choices by: polyphenol-targeted food frequency questionnaire, appetite questionnaire (Council on Nutrition Appetite Questionnaire, CNAQ), questionnaire on food expectations and choices, on culinary practices, supply, and nutritional perceptions. Assessment of diet quality with various scores (DQI, PNNS-GS, DII) and post-hoc analyses. |
| From enrollment to the end of the surveys at 30 day |
| Assessment of physical capacities and physical activity | Assessment of physical capacities and physical activity with the chair rise test, calf circumference measurement and two questionnaires (IPAQ, and RPAQ/ONAPS) aimed at assessing physical activity and sedentary lifestyle. | From enrollment to the end of the surveys at 30 day |
| Assessment of several dimensions of health | Assessment of several dimensions of health: 1) oral health (masticatory performance, number of posterior functional units, GOHAI questionnaire on quality of life related to oral health, EAT-10 questionnaire on dysphagia/swallowing, XI questionnaire on dry mouth and the CIF questionnaire on oral dysfunctions); 2) intestinal health (intestinal transit questionnaire and intestinal comfort questionnaire (IGQ); 3) various aspects of quality of life (stress, fatigue, anxiety, sleep, addictions, etc.). | From enrollment to the end of the surveys at 30 day |
| Assessment of psycho-socio-economic status | Assessment of psycho-socio-economic status: questionnaire on precariousness (EPICES score), loneliness (De Jong Gierveld scale), desired healthy aging, quality of life (CAPS-19 scale), well-being profile, satisfaction and frustration of basic psychological needs. Assessment of personality traits and budget dedicated to food purchases. | From enrollment to the end of the surveys at 30 day |
| Collection of blood and urine samples. | Collection of blood and urine samples. | From enrollment to the end of the surveys at 30 day |
| Centre de Recherche en Nutrition Humaine Rhône-Alpes | Recruiting | Pierre-Bénite | Rhone | 69310 | France |
|
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D005247 | Feeding Behavior |
| ID | Term |
|---|---|
| D001519 | Behavior |
| D001522 | Behavior, Animal |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| D006304 | Health Status |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
| D003710 | Demography |
| D011154 | Population Characteristics |
| D015991 | Epidemiologic Measurements |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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