Critical State of "Remission-Recurrence" of Ulcerative Colitis

Research on the Biological Basis of "Disease-Syndrome-Formula" in the Critical State of "Remission-Recurrence" of Ulcerative Colitis (Joint Application A)

This study will recruit 100 patients with ulcerative colitis in remission for a 6-month non intervention follow-up observation. During the study, their conditions will be recorded truthfully, including general information, disease-related symptoms and signs, inflammatory bowel disease questionnaire, anxiety self-assessment scale, depression self-assessment scale, etc., every month. Collect blood, urine, and stool samples from patients every month for examination. Follow up for each subject until their condition recurs.

Inclusion Criteria:

• Patients who meet the criteria based on the clinical characteristics of ulcerative colitis patients in the "remission recurrence" critical state, combined with clinical symptoms, are diagnosed with ulcerative colitis through imaging, endoscopy, laboratory, and histopathological examinations;
• Patients with comprehensive laboratory testing indicators.

Exclusion Criteria:

• Patients with incomplete case information records;
• Patients who have not completed serological tests;
• Complications including intestinal obstruction, intestinal perforation, toxic megacolon, and severe local stenosis;
• Diagnosed or suspected patients with coexisting uncertain colitis, infectious or ischemic colitis;
• Patients with coexisting local or systemic infections, any malignant diseases, or autoimmune diseases;
• Merge primary diseases such as respiratory, circulatory, neurological, endocrine, and hematological disorders;
• Individuals at risk of developing cancer;
• regnant or lactating women.