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The incidence of DM is unclear in RA but most prior data suggest that DM or insulin resistance in RA has risen because of activation of the immune system and/or RA therapy .
Besides, RA causes joints to become stiff, swollen, and agonizing. As a result, the patient may not want to exercise or move. One study found that 42% of people with RA are not physically active. the aim of this study is To evaluate the glycemic status among RA patients with Type 2 diabetes and its association with disease activity.
Taking the potential link between DM and RA into consideration, detection and control of DM will significantly increase prolonged prognosis and therefore decrease the economic burden of RA patients and death rate. The aim of this research is to examine diabetic RA's glycemic status and to assess the relationship between RA and DM's clinical characteristics as well as the therapy response in RA patients with diagnosed DM. Keeping an eye on glycemic control in RA patients could prevent metabolic and cardiovascular comorbidities in those susceptible patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group 1 | RA patients with Type 2 diabetes |
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| Measure | Description | Time Frame |
|---|---|---|
| Fasting blood glucose | correlation between type 2 diabetes control and rheumatoid arthritis activity | baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Patients above age of 18 years old diagnosed with Rheumatoid Arthritis and DM
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed khedr Nady | Contact | +201097613616 | ahmed.16266234@med.aun.edu.eg | |
| Eman Mohamed Ibrahim, Lecturer | Contact | +201007179120 | emanmibrahem@aun.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Ahmed khedr Nady | Assiut University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assiut university | Asyut | Egypt |
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| Label | URL |
|---|---|
| Wasserman A. Rheumatoid Arthritis: Common Questions About Diagnosis and Management. Am Fam Physician. 2018 Apr 1;97(7):455-462. PMID: 29671563. | View source |
| Almutairi KB, Nossent JC, Preen DB, Keen HI, Inderjeeth CA. The Prevalence of Rheumatoid Arthritis: A Systematic Review of Population-based Studies. J Rheumatol. 2021 May;48(5):669-676. doi: 10.3899/jrheum.200367. Epub 2020 Oct 15. PMID: 33060323. | View source |
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According to result of search
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| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO 3rd, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Kvien TK, Laing T, Meas | View source |
| Schoels M, Knevel R, Aletaha D, Bijlsma JWJ, Breedveld FC, Boumpas DT, Burmester G, Combe B, Cutolo M, Dougados M, Emery P, van der Heijde D, Huizinga TWJ, Kalden J, Keystone EC, Kvien TK, Martin-Mola E, Montecucco C, de Wit M, Smolen JS. Evidence for tr | View source |
| Jiang P, Li H, Li X. Diabetes mellitus risk factors in rheumatoid arthritis: a systematic review and meta-analysis. Clin Exp Rheumatol. 2015 Jan-Feb;33(1):115-21. Epub 2014 Dec 22. PMID: 25535750. | View source |
| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |