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Alkaline phosphatase (ALP), is a metalloenzyme of the plasma membrane. Serum ALP levels in children are closely related to age and gender, many commercial test kits being used in hospitals, are only offering reference values for adults. The aim of this study is to determine serum ALP levels regarding to age, gender and pubertal stage.
Alkaline phosphatase (ALP), is a metalloenzyme of the plasma membrane. Serum ALP levels in children are closely related to age and gender, many commercial test kits being used in hospitals, are only offering reference values for adults. The aim of this study is to determine serum ALP levels regarding to age, gender and pubertal stage Methods: This stuy has been proceeded on children, who have no history for a chronic diseasse or medication and attending to the Keçiören Education and Research Hospital Pediatric Policlinic for routine control between September 2012-September 2013. In order to determine the serum Alkaline Phosphatase levels in children, 1063 (511 male, 552 female) patients were incorporated. Ca, P and vitamin D levels were also evaluated. The ranges of serum ALP levels in both genders according to age has been determined.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Serum Alp Levels In Healthy Turkish Children | Other | This study has been proceeded on children, who have no history for a chronic diseasse or medication and attending to the Keçiören Education and Research Hospital Pediatric Policlinic for routine control between September 2012-September 2013 |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Serum Alkaline Phosphatase Levels | Other | Venous blood was drawn from the patients |
|
| Measure | Description | Time Frame |
|---|---|---|
| Serum Alp Levels In Healthy Turkish Children | mean ALP level was determined for each age and sex and minimum and maximum levels were established. | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Vitamin D insufficiency | Regarding their child hood stage, vitamin D insufficiency were established. | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37731811 | Background | Abhangi KK, Choudhari SR, Butala PB, Goyal SR, Yadav TG. Salivary Total Protein and Alkaline Phosphatase Activity as Biomarkers for Skeletal Maturity and Growth Prediction in Healthy Children: An In Vivo Study. Int J Clin Pediatr Dent. 2023 Jul-Aug;16(4):603-607. doi: 10.5005/jp-journals-10005-2629. | |
| 29494096 | Background |
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| ID | Term |
|---|---|
| D007014 | Hypophosphatasia |
| D014808 | Vitamin D Deficiency |
| ID | Term |
|---|---|
| D008664 | Metal Metabolism, Inborn Errors |
| D008661 | Metabolism, Inborn Errors |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
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Prospective study.
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not able
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| Lala V, Zubair M, Minter DA. Liver Function Tests. 2023 Jul 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK482489/ |
| 32142736 | Background | Lu KL, Xie SS, Liu E, Yu XM, Wang L, Yang ZY, Xiong Q, Luo XG, Yang W, Liao W, Zhang YP. Age-wise trends in alkaline phosphatase activity in 167,625 Chinese children aged 0-18 years. Clin Biochem. 2020 May;79:34-40. doi: 10.1016/j.clinbiochem.2020.03.001. Epub 2020 Mar 3. |
| 32796205 | Background | Topal I, Gumus B. Can Bone-Specific Alkaline Phosphatase and Osteocalcine Levels Be Used to Determine the Age in Children? Am J Forensic Med Pathol. 2020 Sep;41(3):182-187. doi: 10.1097/PAF.0000000000000555. |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D001361 | Avitaminosis |
| D003677 | Deficiency Diseases |
| D044342 | Malnutrition |
| D009748 | Nutrition Disorders |