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| Name | Class |
|---|---|
| Denise Battaglini | UNKNOWN |
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This single-center observational study aims to assess the effects of continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy on lung recruitment using electrical impedance tomography (EIT) in spontaneously breathing patients admitted to the intensive care unit.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Continuous high-frequency oscillation (CHFO) and continuous positive expiratory pressure (CPEP) therapy | Procedure | During application of CPEP and CHFO, EIT is monitored. |
| Measure | Description | Time Frame |
|---|---|---|
| To assess changes in systemic oxygenation | Arterial partial pressure of oxygen (PaO2, mmHg) and PaO2/FiO2 ratio (mmHg) | Immediately before starting treatment (PEP or CHFO), immediately after the end of treatment, at 30 minutes after the end of treatment and at 60 minutes after the end of treatment |
| Changes in lung recruitment using EIT | Absolute reduction in the percentage (%) of lung volume collapse assessed with the electrical impedance tomography (EIT) | Immediately before starting treatment (PEP or CHFO), immediately after the end of treatment, at 30 minutes after the end of treatment and at 60 minutes after the end of treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Mean arterial pressure, mmHg | Heart rate as measured by continuous pressure monitoring | Immediately before starting treatment (PEP or CHFO), immediately after the end of treatment, at 30 minutes after the end of treatment and at 60 minutes after the end of treatment |
| Heart rate min-1 |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who are spontaneously breathing and admitted to the intensive care unit
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Denise Battaglini, MD, PhD | Contact | +39-0105554970 | battaglini.denise@gmail.com | |
| Lorenzo Ball, MD, PhD | Contact | +39-0105554970 | lorenzo.ball@unige.it |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UO Clinica Anestesiologica e Terapia Intensiva, IRCCS Ospedale Policlinico San Martino | Genova | GE | 16132 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37097986 | Result | Jonkman AH, Alcala GC, Pavlovsky B, Roca O, Spadaro S, Scaramuzzo G, Chen L, Dianti J, Sousa MLA, Sklar MC, Piraino T, Ge H, Chen GQ, Zhou JX, Li J, Goligher EC, Costa E, Mancebo J, Mauri T, Amato M, Brochard LJ; Pleural Pressure Working Group (PLUG). Lung Recruitment Assessed by Electrical Impedance Tomography (RECRUIT): A Multicenter Study of COVID-19 Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2023 Jul 1;208(1):25-38. doi: 10.1164/rccm.202212-2300OC. | |
| 31410738 |
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Heart rate as measured by continuous electrocardiogram monitoring |
| Immediately before starting treatment (PEP or CHFO), immediately after the end of treatment, at 30 minutes after the end of treatment and at 60 minutes after the end of treatment |
| Result |
| Longhini F, Maugeri J, Andreoni C, Ronco C, Bruni A, Garofalo E, Pelaia C, Cavicchi C, Pintaudi S, Navalesi P. Electrical impedance tomography during spontaneous breathing trials and after extubation in critically ill patients at high risk for extubation failure: a multicenter observational study. Ann Intensive Care. 2019 Aug 13;9(1):88. doi: 10.1186/s13613-019-0565-0. |
| 34063429 | Result | Battaglini D, Caiffa S, Gasti G, Ciaravolo E, Robba C, Herrmann J, Gerard SE, Bassetti M, Pelosi P, Ball L, On Behalf Of The Gecovid Group. An Experimental Pre-Post Study on the Efficacy of Respiratory Physiotherapy in Severe Critically III COVID-19 Patients. J Clin Med. 2021 May 15;10(10):2139. doi: 10.3390/jcm10102139. |
| 29485340 | Result | Reychler G, Uribe Rodriguez V, Hickmann CE, Tombal B, Laterre PF, Feyaerts A, Roeseler J. Incentive spirometry and positive expiratory pressure improve ventilation and recruitment in postoperative recovery: A randomized crossover study. Physiother Theory Pract. 2019 Mar;35(3):199-205. doi: 10.1080/09593985.2018.1443185. Epub 2018 Feb 27. |
| 31113857 | Result | Rowley DD, Malinowski TP, Di Peppe JL, Sharkey RM, Gochenour DU, Enfield KB. A Randomized Controlled Trial Comparing Two Lung Expansion Therapies After Upper Abdominal Surgery. Respir Care. 2019 Oct;64(10):1181-1192. doi: 10.4187/respcare.06812. Epub 2019 May 21. |
| ID | Term |
|---|---|
| D012131 | Respiratory Insufficiency |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
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| ID | Term |
|---|---|
| C075403 | cholesterylphosphorylethylpyridinium |
| D013812 | Therapeutics |
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