Psychosocial and Functional Factors in AxSpA

Psychosocial and Functional Interactions in the Characterization of Axial Spondyloarthritis

This observational, cross-sectional study aims to characterize patients with axial spondyloarthritis (AxSpA) from a biopsychosocial perspective. The study examines the relationships between psychosocial factors (such as pain catastrophizing, kinesiophobia, and fear-avoidance beliefs) and clinical indicators of disease progression, including functional limitations and disease activity. The primary objective is to identify psychosocial predictors of functionality and disease activity in AxSpA patients, which may guide more personalized therapeutic interventions. Findings could provide insights into the combined effects of physical and psychological aspects on disease management, promoting a holistic approach to AxSpA care.

Inclusion Criteria:

• Adults (18 years and older) diagnosed with axial spondyloarthritis (AxSpA) based on the Assessment of SpondyloArthritis International Society (ASAS) criteria.
• Experiencing symptoms of axial or peripheral involvement.
• A minimum score of 3/10 on the Numeric Pain Rating Scale (NPRS) during the initial assessment.

Exclusion Criteria:

• Individuals with other rheumatic or musculoskeletal conditions affecting the spine or joints (e.g., rheumatoid arthritis or osteoarthritis).
• History of spinal surgery or joint replacement surgery.
• Receipt of corticosteroid injections or other pharmacological treatments targeting inflammation within six weeks prior to data collection.
• Any ongoing medico-legal conflicts that could interfere with study participation.