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Concha bullosa (CB) refers to the condition where the middle turbinate's interior is aerated (making the turbinate wide and thick). CB can narrow the middle meatus and the ostiomeatal complex. In adults suffering from chronic sinusitis, the prevalence of CB is approximately 34%. The most common treatment method for CB is turbinate crushing. This is considered a conservative treatment that preserves the mucous membranes relatively intact without opening the interior of the turbinate. Another fairly common method is the removal of the lateral part of the bullous middle turbinate. Opening the CB and removing the lateral part of the middle turbinate can lead to adhesions between the middle turbinate and the lateral wall of the nose. These adhesions can impede airflow and narrow or completely close the ostium or the surgically created middle meatal antrostomy. Crushing the CB is technically easier and possibly a less traumatic procedure. However, it is suspected that some of these crushed bullous turbinates may refill. The development of a mucocele is another potential issue. Crushing might be a better option compared to resection in the long term. Preserving the mucous membranes during crushing may reduce the formation of adhesions, which are sometimes seen after resection of the middle turbinate. The purpose of the study is to investigate the long-term benefits and side effects of CB treatment methods. The study will include 60 patients undergoing a basic Functional Endoscopic Sinus Surgery (FESS) procedure due to recurrent or chronic maxillary sinusitis. The patients will be randomized, with 31 undergoing resection and 31 undergoing crushing. Before the procedure, patients will undergo a CT scan (NSO-TT) and symptom evaluation through various questionnaires. All patients will also undergo nasoscopy.
One year after the procedure, the patients' conditions will be reassessed (questionnaires, nasoscopy, NSO-TT only if necessary), including the need for revision surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| crushing | Active Comparator | Concha bullosa crushing group |
|
| resection | Active Comparator | Concha bullosa resection group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Concha bullosa crushing | Procedure | Concha bullosa crushing |
| |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative SNOT-22 | postoperative SNOT-22 score | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| LM endoscopy score | LM endoscopy score | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Antibiotics usage postoperatively | Antibiotics usage postoperatively | 1 year |
Inclusion Criteria:
chronic or recurrent rhinosinusitis
3 months of regular nasal corticosteroid usage
No prior endoscopic procedures of the paranasal sinuses
EPOS criteria for CRS are met: inflammation of the paranasal sinuses with at least 2 symptoms, one of which must be nasal obstruction/congestion or nasal discharge (anterior/posterior):
facial pain/pressure in the facial area
reduced or lost sense of smell SNOT-22 25 or higher
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| Name | Affiliation | Role |
|---|---|---|
| Markus Lilja, PhD | Helsinki University Central Hospital | Study Director |
| Mario Järvekülg, MD | Helsinki University Central Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Helsinki University Hospital Ear Clinic | Helsinki | Uusimaa | 00130 | Finland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15518100 | Background | Dogru H, Uygur K, Tuz M. Concha bullosa squeezer for turbinoplasty (Dogru forceps). J Otolaryngol. 2004 Apr;33(2):111-3. doi: 10.2310/7070.2004.02112. No abstract available. |
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According to the data protection regulations, patients' personal data cannot be shared publicly in Finland.
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| Concha bullosa resection |
| Procedure |
Concha bullosa resection |
|
| ID | Term |
|---|---|
| D012852 | Sinusitis |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D010254 | Paranasal Sinus Diseases |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
| D010038 | Otorhinolaryngologic Diseases |
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