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| ID | Type | Description | Link |
|---|---|---|---|
| ZDYF2024SHFZ064 | Other Grant/Funding Number | Hainan Provincial Department Of Science and Technology | |
| 82360673 | Other Grant/Funding Number | National Natural Science Foundation of China | |
| XRC2022005 | Other Grant/Funding Number | Hainan Medical University |
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| Name | Class |
|---|---|
| The Second Affiliated Hospital of Hainan Medical University | OTHER |
| Xuanwu Hospital, Beijing | OTHER |
| Fudan University | OTHER |
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This is a community-based prospective cohort study in Hainan Province, China. The study was initialized in 2023 and included older residents for longitudinal follow-up. The research aims to identify risk factors as well as health and social outcomes that are associated with cognitive impairment in elderly populations, and independently develop AI-assisted software and applications for cognitive enhancement and physical rehabilitation training.
This is a community-based prospective cohort study in Hainan Province, China. Subjects are individuals aged 60 years and above who have lived in the communities for more than six months and have signed informed consent. The research have been initialed in 2023 and aims to identify the risk factors associated with cognitive impairment, to develop software for cognitive enhancement and physical rehabilitation training. The study includes three steps: first, to conduct cognitive function screening in 16 communities in four districts (Xiuying, Meilan, Longhua, and Qiongshan) of Haikou City and establish a database for the elderly in tropical regions; second, to identify risk factors associated with cognitive impairment in the elderly population; finally, to independently develop a software for cognitive function enhancement and physical rehabilitation training.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No Intervention: Observational Cohort | Other | There were no interventions in our cohort. The subjects of our cohort were and will be followed up at the regular intervals. |
| Measure | Description | Time Frame |
|---|---|---|
| The prevalence and incidence of cognitive impairment base on the communities | Mild cognitive impairment was measured using a Chinese version Mini-Mental State Examination, which was collected by questionnaire. The minimum value of the Mini-Mental State Examination is 0, and the maximum value is 30, the higher the score, the better the cognition outcome. | An average of 1 to 2 years |
| The prevalence and incidence of dementia using a population-based survey | Dementia was determined by diagnosis of hospitalization or Clinical Dementia Rating Scale (Montreal Cognitive Assessment, MoCA). The minimum value of the MoCA is 0, and the maximum value is 30, the higher the score, the better the outcome. In addition, subtypes of dementia will be based on the specific clinical diagnosis. | An average of 1 to 2 years |
| The conversion rate of normal to cognitive impairment | Percentage of enrolled population that convert from normal to cognitive impairment | An average of 1 to 2 years |
| The conversion rate of cognitive impairment to dementia | Percentage of enrolled population that convert from cognitive impairment to dementia | An average of 1 to 2 years |
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Inclusion Criteria:
Exclusion Criteria:
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Community residents aged 60 years or older in Hainan Province, China
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jindong Ding Petersen, PHD. | Contact | 089866893772 | dingjindong@muhn.edu.cn |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hainan Medical University | Recruiting | Haikou | Hainan | 571199 | China |
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| D003704 | Dementia |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
| D001927 | Brain Diseases |
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Plan to collect blood samples from some participants
| D002493 |
| Central Nervous System Diseases |
| D009422 | Nervous System Diseases |