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Chronic obstructive pulmonary disease (COPD) is a worldwide public health challenge because of high prevalence and related disability and mortality (1).
Acute exacerbation of COPD (AECOPD), defned as the worsening of respiratory symptoms and requirement of additional clinical treatment, it reduces lung function and quality of life, and is accompanied by an increased disease-related burden, high hospital mortality and poor outcome (2).
Chronic obstructive pulmonary disease frequently coexists with other chronic diseases, namely comorbidities. They negatively impact prognosis, exacerbations and quality of life in COPD patients. Local and systemic inflammation have been proposed as having a potential role in explaining the association between COPD and these comorbidities (3).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COPD patients in ICU with high risk of mortality (non survivors) | COPD patients on NIV / MV | ||
| COPD patients in ICU with low risk of mortality ( survivors ) | COPD patients on NIV / MV |
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| Measure | Description | Time Frame |
|---|---|---|
| Clinical Presentation and Outcome of COPD Patients With Acute Exacerbation Attending Sohag University Hospital | Detection which patient with COPD exacerbation has more risk of survival or mortality | 1 year |
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Inclusion Criteria:
patients with a confirmed COPD diagnosis according to (GOLD) guidelines, presented with acute exacerbation
Exclusion Criteria:
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patients aged more than 18 years with a confirmed COPD diagnosis according to (GOLD) guidelines, presented with acute exacerbation
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mona A Hussien, Resident doctor | Contact | 01152232471 | mona_abdelaleem_post@med.sohag.edu.eg | |
| Hamdy A Mohammaden, Professor doctor | Contact |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 17823358 | Background | Fabbri LM, Boschetto P, Mapp CE; Global Initiative for Chronic Obstructive Lung Disease; Global Initiative for Asthma Management and Prevention. COPD guidelines: the important thing is not to stop questioning. Am J Respir Crit Care Med. 2007 Sep 15;176(6):527-8. doi: 10.1164/rccm.200706-854ED. No abstract available. | |
| 15283307 |
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| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| ID | Term |
|---|---|
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
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| Bateman ED, Feldman C, O'Brien J, Plit M, Joubert JR; COPD Guideline Working Group of the South African Thoracic Society. Guideline for the management of chronic obstructive pulmonary disease (COPD): 2004 revision. S Afr Med J. 2004 Jul;94(7 Pt 2):559-75. |
| 28918970 | Background | Corrections. Lancet Respir Med. 2017 Oct;5(10):e30. doi: 10.1016/S2213-2600(17)30336-3. Epub 2017 Sep 14. No abstract available. |
| 102509 | Background | Nakai T, Ueda M, Takeda R. Effects of calcium and magnesium ions on the interaction of corticosterone with rat brain cytosol receptor(s). Endocr Res Commun. 1978;5(2):81-90. doi: 10.3109/07435807809089010. |
| 1900164 | Background | Hand D. National Boards lose control of funding. Nurs Stand. 1991 Feb 13-19;5(21):20. No abstract available. |
| D020969 |
| Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |