Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The objective of this learning clinical study is to evaluate the effects of formulation chemistry on gingivitis.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 0.76% Sodium Monofluorophosphate | Sham Comparator | 0.76% Sodium Monofluorophosphate |
|
| 0.454% Stannous Fluoride | Active Comparator | 0.454% Stannous Fluoride |
|
| 0.454% Stannous Fluoride, 4.7 pH | Experimental | 0.454% Stannous Fluoride, 4.7 pH |
|
| 0.454% Stannous Fluoride, 5.8 pH | Experimental | 0.454% Stannous Fluoride, 5.8 pH |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 0.76% Sodium Monofluorophosphate Dentifrice | Drug | Whole mouth brushing with a toothpaste, twice daily for the duration of the study. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number Bleeding Sites | Number of bleeding sites derived from the Löe-Silness Gingivitis Evaluation based on a validated assessment of gingival health looking at inflammation and bleeding based on a 4 point range 0 (normal gingiva) to 3 (severe inflammation). | 3 months, 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Löe-Silness Gingivitis Evaluation | Löe-Silness Gingivitis Evaluation is a validated assessment of gingival health looking at inflammation and bleeding based on a 4 point range 0 (normal gingiva) to 3 (severe inflammation). | 3 months, 1 month |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Silverstone Research | Las Vegas | Nevada | 89146 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D005882 | Gingival Diseases |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 0.454% Stannous Fluoride Dentifrice | Drug | Whole mouth brushing with a toothpaste, twice daily for the duration of the study. |
|