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The primary aim of our study is to evaluate the presence of stress urinary incontinence in postmenopausal patients with and without osteoporosis, determine its impact on quality of life, and explore its relationship with sarcopenia.
One hundred postmenopausal women, aged 50-75, who applied to the Physical Therapy and Rehabilitation outpatient clinic at Beylikdüzü State Hospital and have Dual-X-ray Absorptiometry (DXA) measurements taken within the last 6 months, including both osteoporotic and non-osteoporotic patients, will be included in the study. Sociodemographic data such as age, gender, height, weight, and BMI will be recorded. DXA results, including femoral neck and L1-L4 T-scores and BMD values, will be obtained. Patients will be asked about osteoporosis treatment, presence of fecal incontinence, constipation, and medication use. Stress urinary incontinence will be determined through a questionnaire, and its impact on quality of life will be assessed using the Incontinence Quality of Life Scale. In the second phase, sarcopenia will be evaluated according to the Asian Working Group for Sarcopenia (AWGS) criteria by assessing skeletal muscle mass (via bioelectrical impedance analysis), handgrip strength, and the 5-times sit-to-stand test.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Postmenopausal osteoporosis | Postmenopausal osteoporosis is diagnosed using Dual-X-ray Absorptiometry (DXA), which measures bone mineral density (BMD) and provides a T-score. A T-score of -2.5 or lower confirms the diagnosis of osteoporosis. |
| |
| Postmenopausal non-osteoporotic women | These women maintain normal bone mineral density (BMD) levels, typically assessed using Dual-X-ray Absorptiometry (DXA). A T-score above -1.0 is considered normal. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| No intervention | Diagnostic Test | No intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| Presence of Stress Urinary Incontinence: | Stress urinary incontinence (SUI) is the involuntary leakage of urine during physical activities that increase abdominal pressure, such as coughing, sneezing, or lifting. In this study, the presence of SUI will be determined through a questionnaire that asks participants about symptoms and frequency of urine leakage during such activities. | 0 day |
| Incontinence Quality of Life Scale (I-QOL): | The I-QOL is a validated questionnaire that measures the impact of urinary incontinence on a patient's quality of life. It assesses how incontinence affects daily activities, social interactions, and emotional well-being. Higher scores indicate better quality of life, while lower scores suggest that incontinence has a more significant negative impact on the patient's day-to-day functioning. | 0 day |
| Skeletal Muscle Mass: | Measured by bioelectrical impedance analysis (BIA), this assesses the amount of muscle tissue in the body. Low skeletal muscle mass indicates sarcopenia. | 0 day |
| Handgrip Strength | This is a simple test to measure muscle strength. Reduced handgrip strength is a sign of sarcopenia. | 0 day |
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Inclusion Criteria:
Femoral neck and L1-L4 T-scores of -1 and above will be included in the control group (non-osteoporotic).
Femoral neck and L1-L4 T-scores of -2.5 and below will be included in the osteoporosis group.
Exclusion Criteria:
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Postmenopausal women
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Büşra Şirin Ahısha, MD | Contact | (0212) 856 27 40 | bsrn080@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beylikdüzü State Hospital | Recruiting | Istanbul | 34147 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41935994 | Derived | Sirin Ahisha B, Paker N, Kesiktas N, Ersoy S, Bugdayci ND, Ahisha YC. Stress urinary incontinence and sarcopenia in postmenopausal osteoporosis: the intersection of muscle loss and pelvic dysfunction. World J Urol. 2026 Apr 5;44(1):276. doi: 10.1007/s00345-026-06392-3. |
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| ID | Term |
|---|---|
| D015663 | Osteoporosis, Postmenopausal |
| ID | Term |
|---|---|
| D010024 | Osteoporosis |
| D001851 | Bone Diseases, Metabolic |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
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| D008659 |
| Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |