Effect of Consuming a Combination of Probiotic Strains on Postpartum Depression

Multicenter, Randomized, Double-blind, Parallel-group Controlled Nutritional Intervention Study to Evaluate the Effect of a Combination of Probiotic Strain on Postpartum Depression

The objective of this trial is to evaluate the effect of consuming a combination of Lactobacillus during the pregnancy and lactation period on the incidence of postpartum depression.

The mood disorders such as postpartum depression have a very high incidence. There is a relationship between a woman's microbiota and the risk of postpartum depression.

The possibility of influencing the microbiota through probiotic treatments opens a door to the prevention and/or treatment of postpartum depression.

Therefore, the objective of this trial is to evaluate the effect of consuming a combination of Lactobacillus during the pregnancy and lactation period on the incidence of postpartum depression.

Inclusion Criteria:

• Pregnant who is between 28-32 weeks of gestation.
• Normal development of pregnancy.
• Singleton pregnancy.
• Score ≥12 scale Postpartum depression questionnaire Edinburgh.
• Pregnant who has the firm intention of breastfeeding her child for at least the first month.
• Sign the Informed Consent.

Exclusion Criteria:

• Have any breast pathology that makes it difficult or impossible to breastfeed.
• Consume other probiotic supplements during the study.
• History of serious mental disorders other than affective disorders, whether or not currently under pharmacological treatment.
• Low expectation of adherence to the study protocol.
• Pharmacological treatment incompatible with the study.
• Non-compliance with the study protocol.