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This study was designed to compare between the effect of high intensity interval training (HIIT) and moderate intensity continuous training (MICT) on soluble ST2 biomarkers among chronic heart failure patients, also measure the improvement in the quality of life with different modes of exercise and with of it is more benifitial for the heart failure patient
The data concerned with the study including soluble ST2 biomarker levels, ejection fraction and MLHFQ was measured before and after twelve weeks of treatment.In this study a total sixty male patients with chronic heart failure NYHA class (I &II) were selected from the outpatient clinic, El-Demerdash hospital, Ain-shams University. Their age ranged from 50-60 years. Patients were randomly assigned into two groups, group A receiving HIIT along with prescribed medical treatment and group B receiving MCT along with prescribed medical treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group A | Experimental | high intensity interval training |
|
| group B | Experimental | moderate intensity continuous training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HIITS | Other | Frequency: HIIT will be in 2 supervised sessions per week for 12 weeks on the treadmill. session duration from 30-40 min including the waming up and cooling down Intensity: HIIT included 4 minute intervals aiming 60-85% of heart rate reserve |
| Measure | Description | Time Frame |
|---|---|---|
| soluble ST2 biomarker level | sample was taken at the cubited vein at the beginning of the program and also at its end | before the start of the trail and at the end of the trail 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| ejection fraction | Left ventricular systolic dysfunction was assessed using the ejection fraction by 2D simpson method | before the start of the trail and at the end of the trail 3 months |
| mannisota of daily living questionnaire score |
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Inclusion Criteria:
The patients selection was according to the following criteria:
Exclusion Criteria:
Patients who had met one of the following criteria were excluded from the study:
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| Name | Affiliation | Role |
|---|---|---|
| Donia M Elmasry, Doctorate | Cairo University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of physical therapy Cairo University | Giza | 0000 | Egypt |
study protocol and final results
August 2024 till December 2024
researchers
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Sep 11, 2022 | Oct 15, 2024 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| MICT | Other | Frequency: Moderate continuous training is scheduled 2 times per week for 12 weeks. Intensity: exercise had been applied on the treadmill with 40%-59% of heart rate reserve) session duration from 30-40 min including the warming up and cooling down |
|
The twenty one item questionnaire was usedfrom 0 (none) to 5 (very much). It provides a total score (range 0-105, from best to worst HRQoL), as well as scores for two dimensions, physical (8 items, range 0-40) and emotional (5 items, range 0-25). The other eight items (of the total of 21) are only considered for the calculation of the total score.
| before the start of the trail and at the end of the trail 3 months |
| peak exercise response | monitoring the peak exercise response | before the start of the trail and at the end of the trail 3 months |