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The goal of this clinical trial is to investigate the role of segmentectomy in clinical T1c (2-3 cm) non-small cell lung cancer (NSCLC). The main questions we aim to answer are:
Researchers will compare segmentectomy and lobectomy in terms of overall and recurrence free survival.
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Segmentectomy | Experimental | Pulmonary anatomic segmentectomy with mediastinal nodal dissection |
|
| Lobectomy | Active Comparator | Pulmonary lobectomy with mediastinal nodal dissection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Segmentectomy | Procedure | Pulmonary anatomic segmentectomy with mediastinal nodal dissection via VATS, RATS or open approach. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Survival Survival | Overall and recurrence free survival | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Complication rate associated with surgery | 90 days | |
| Mortality rate | mortality rate associated with surgery | 90 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Akif Turna, MD, PhD | Contact | +905052581581 | aturna@iuc.edu.tr | |
| Melek Ağkoç, MD | Contact | +905348108485 | melek.agkoc1@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Akif Turna, MD, PhD | Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty | Istanbul | 34198 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D002289 | Carcinoma, Non-Small-Cell Lung |
| ID | Term |
|---|---|
| D002283 | Carcinoma, Bronchogenic |
| D001984 | Bronchial Neoplasms |
| D008175 | Lung Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
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| ID | Term |
|---|---|
| D015412 | Mastectomy, Segmental |
| D038481 | Anterior Temporal Lobectomy |
| ID | Term |
|---|---|
| D008408 | Mastectomy |
| D013514 | Surgical Procedures, Operative |
| D019635 | Neurosurgical Procedures |
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| Lobectomy | Procedure | Pulmonary lobectomy with mediastinal nodal dissection via VATS, RATS or open approach. |
|
| D013899 |
| Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |