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| Name | Class |
|---|---|
| iThera Medical GmbH | INDUSTRY |
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During this IIT, the MSOT (Multispectral Optoacoustic Tomography ) Acuity Echo will be used to scan participants with Peripheral Arterial Disease assess MSOT Multispectral Optoacoustic Tomography (single-wavelength and hemoglobin-related parameters) in the Tibialis Anterior, and flexor hallucis brevis, at multiple time-points before, during and after interventional Lower Extremity Revascularization (LER ).
Primary aim of the study ist the Comparison of the difference between oxygenated, deoxygenated hemoglobin and oxygenation in the tibialis anterior, and flexor hallucis brevis, at multiple time-points before, during and after interventional Lower Extremity Revascularization.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MSOT Multispectral Optoacoustic Tomography | Device | MSOT Multispectral Optoacoustic Tomography, single-wavelength, HbT, Hb, HbO2, collagen and mSO2 (700-1.100 nm wavelength range, in 10 nm increments) in the tibialis anterior and flexor hallucis brevis, at multiple time-points before, during and after interventional LER Lower Extremity Revascularization . |
| Measure | Description | Time Frame |
|---|---|---|
| MSOT Multispectral Optoacoustic Tomography, | single-wavelength, HbT, Hb, HbO2, collagen and mSO2 (700-1.100 nm wavelength range, in 10 nm increments) in the tibialis anterior and flexor hallucis brevis, at multiple time-points before, during and after interventional LER Lower Extremity Revascularization . | baseline pre LER, 30 minutes post LER, 24 hours post LER, 48hours post LER |
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Inclusion Criteria:
• Written consent of the participant after being informed
Exclusion Criteria:
• Participants with previous LER on the same leg
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• Participants with PAD stage 4 - 6 (Rutherford) with indication for interventional LER
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Astrid Friedel | Contact | 031638578017 | astrid.friedel@medunigraz.at |
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| ID | Term |
|---|---|
| D058729 | Peripheral Arterial Disease |
| ID | Term |
|---|---|
| D050197 | Atherosclerosis |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |
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| D002318 |
| Cardiovascular Diseases |
| D016491 | Peripheral Vascular Diseases |