Evaluation of Perfusion and Oxygenation in Muscle of Patients With PAD Undergoing LER

Evaluation of Perfusion and Oxygenation in Muscle of Patients With PAD Undergoing LER

During this IIT, the MSOT (Multispectral Optoacoustic Tomography ) Acuity Echo will be used to scan participants with Peripheral Arterial Disease assess MSOT Multispectral Optoacoustic Tomography (single-wavelength and hemoglobin-related parameters) in the Tibialis Anterior, and flexor hallucis brevis, at multiple time-points before, during and after interventional Lower Extremity Revascularization (LER ).

Primary aim of the study ist the Comparison of the difference between oxygenated, deoxygenated hemoglobin and oxygenation in the tibialis anterior, and flexor hallucis brevis, at multiple time-points before, during and after interventional Lower Extremity Revascularization.

Inclusion Criteria:

• • Written consent of the participant after being informed

  • Adults above 18 years
  • Participants with PAD stage 4 - 6 (Rutherford) with indication for interventional LER

Exclusion Criteria:

• • Participants with previous LER on the same leg

  • Participants less than 18years
  • Pregnancy
  • Participants with tattoos in the scan area
  • Participants with no clinical indication for interventional LER
  • Missing consent form