This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.

The Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.

The aim of this study is three-fold: 1. To evaluate the clinical performance of glass ionomer fissure sealants and resin fissure sealants when placed immediately after or one week following the application of silver fluoride on permanent molars affected by Molar-Incisor Hypomineralization in high caries-risk children. 2. To compare the effects of rinsing off the silver fluoride or not rinsing it off (blot-drying with cotton pellet) on sealant retention when the sealant is placed immediately after silver fluoride application, and 3. To measure the desensitizing effect of fissure sealant application following silver fluoride treatment on hypersensitive MIH molars.

Teeth will be randomized in a parallel design based on the application of restoration time (immediate or one week later), sealant material type (resin or glass ionomer), and for immediate applications, the condition of silver fluoride before restoration (dried with cotton or rinsed gently). A total of 216 permanent molars will be included in the study.

Randomization of molar teeth into six groups according to the restoration time, dental restorative material type, and conditions:

Inclusion Criteria:

• Patients and their parents who consent to participate and have signed the informed consent form.
• Patients with at least one permanent molar diagnosed with molar incisor hypomineralization based on EAPD guidelines.
• Fully erupted teeth with ICDAS I or II lesions that necessitate the application of fissure sealants.
• Teeth displaying demarcated opacities on the occlusal surface and at least one additional surface.

Exclusion Criteria:

• Teeth that have existing restorations or cavities.
• Patients currently receiving orthodontic treatment.
• Patients who are uncooperative during dental procedures.
• Teeth affected by dental fluorosis or enamel defects associated with specific syndromes.
• Children with systemic conditions requiring ongoing medication.