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| ID | Type | Description | Link |
|---|---|---|---|
| Self-financed | Other Identifier | Self-financed |
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LED Therapy for third molar surgery
LED Therapy using 830 nm in the mandibular third molar surgery
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group | Sham Comparator | The irradiation protocol was the same as that of the experimental group, and the light source used was simulated light. After surgery, patients took ibuprofen 0.3 g bid for 3 consecutive days, metronidazole 0.1 g tid, and cefaclor 0.375 g bid for 7 consecutive days. |
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| Treatment Group | Experimental | LED light was irradiated 4 times (830 nm, 50 mW/cm2, 60 J/cm2, 1200 s) on D1 (before and after surgery), D2, and D3, which was extraoral irradiation. After surgery, ibuprofen 0.3 g bid for 3 consecutive days, metronidazole 0.1 g tid, and cefaclor 0.375 g bid for 7 consecutive days were taken. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| photobiomodulation | Device | 830 nm LED was used to irradiate the post-extraction area |
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| Measure | Description | Time Frame |
|---|---|---|
| Pain | Visual Analogue Scale,VAS | Day 7 |
| Swelling | Facial swelling was measured in 2 planes: the distance between the tragus and lip commissure and the distance between the gonion and external canthus of the eye. | Day 3; Day 7 |
| Trismus | Trismus was evaluated by measuring the maximum mouth opening between the edges of the upper and lower central incisors with a calibrated ruler. | Day 3; Day 7 |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life score | OHIP-14 Scale | Day 3; Day 7 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yanjun Jane Dan, Medical Doctor | Contact | +86 15901940897 | 15901940897@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Huashan Hospital Affiliated to Fudan University | Shanghai | Shanghai Municipality | 200040 | China |
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| ID | Term |
|---|---|
| D028022 | Low-Level Light Therapy |
| D000900 | Anti-Bacterial Agents |
| ID | Term |
|---|---|
| D053685 | Laser Therapy |
| D013812 | Therapeutics |
| D010789 | Phototherapy |
| D000890 | Anti-Infective Agents |
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Patients who underwent mandibular third molar extraction
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This study was a double-blind study in which the patient, the surgeon, and the statistician were all unaware of whether the patient received treatment or a placebo control light . Only the operator using the LED light was aware of this information. The assigned group was recorded on sealed and opaque envelopes. These cards were prepared by an independent person who was not involved in the study protocol. Once the patient underwent extraction and agreed to participate in this trial, this independent person opened the envelope to reveal the allocation.
| Antibiotic |
| Drug |
ibuprofen 0.3 g bid for 3 days, metronidazole 0.1 g tid, and cefaclor 0.375 g bid for 7 days after surgery |
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| D045506 |
| Therapeutic Uses |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |