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Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix derivatives in vertical bone defects Study of the effectiveness of the application of guided tissue regeneration in vertical bone defects with Barrier membrane and Barrier membrane and autogenous platelet-rich plasma
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PRP alone | Active Comparator |
| |
| EMD Alone | Active Comparator |
| |
| GTR (barrier membrane) | Active Comparator |
| |
| GTR(barrier membrane and PRP) | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PRP( platelet rich plasma) | Procedure | regenerative therapy with PRP for vertical bone defects |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Probing depth in mm | 6 months | |
| Level of Margo Gingivalis in mm | 6 months | |
| Clinical attachment level in mm | 6 months | |
| The distance from the ECJ to the base of the bone defect in mm | 6 months | |
| The distance from the ECJ to the apex of the bone defect in mm | 6 months | |
| The width of the bone defect in mm | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical University - Varna | Varna | Varna | 9000 | Bulgaria |
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| EMD (Enamel Matrix Derivative) |
| Procedure |
regenerative therapy with EMD for vertical bone defects |
|
| Guided Tissue Regeneration (barrier membrane) | Procedure | guided tissue regeneration with barrier membrane alone for vertical bone defects |
|
| Guided Tissue Regeneration(barrier membrane and PRP) | Procedure | guided tissue regeneration with barrier membrane and PRP for vertical bone defects |
|
| ID | Term |
|---|---|
| C092710 | emerin |
| D048091 | Guided Tissue Regeneration |
| ID | Term |
|---|---|
| D019651 | Plastic Surgery Procedures |
| D013514 | Surgical Procedures, Operative |
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